Path Test 3: Blood Vessels
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3 Layers of Blood Vessels
Intima consists of ?
What separates the intima and media?
Internal Elastic Lamina (IEL)
What separates the media and adventita?
External Elastic Lamina
Name 3 Blood Vessel Congenital Abnormalities
- Berry aneurysms
- Arteriovenous fistulas
- Fibromuscular dysplasia
Attenuated media at the Circle of Willis, can rupture
Berry aneurysm (Congenital Abnormallity)
Connecting arteries and veins with no capillaries. Can cause high-output cardiac failure.
Focal irregular thickening of medium an large arteries in young women. Can cause renovascular hypertension.
Fibromuscular dysplasia causes _______ in young women.
Hypertensive Valvular Disease affects what percentage of the population?
Name 2 cardiac complications from HTN.
- Pressure overload
- Ventricular hypertrophy
Essential hypertension is associated with increased risk of
Malignant Hypertension (5%)
Complications of malignant hypertension
- Renal failure
- Retinal hemorrhage/exudates
Name 3 types of Arteriosclerosis
- Monckeberg medial calcifcation sclerosis
Hyaline Arteriosclerosis is caused by (2)
Leakage of plasma contents across injured endothelial cells
Hyaline Arteriolosclerosis results in
- Severe HTN
- SMC, duplicated basement membrane
Severe HTN =
- S= Hyperplastic Arteriolosclerosis
- B= Hyaline arteriosclerosis
Structure of atheromatous plaque
- Fibrous cap
- Necrotic Center with cholesterol center
Risk Factors for Thoracic Aortic Aneurysm (3)
- Marfan Syndrome
Major risk factor for aortic dissection.
Aorta shows medial hypertotrophy of vasa vasorum with degenerative ECM
Marfan's Syndrome is an ___ inheritance with missense mutations in ______gene (15q21)
Malignant vascular tumor
Kaposi Sarcoma is associated with
- Eastern European men
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