n304 quiz 2

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buckwild
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184385
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n304 quiz 2
Updated:
2012-11-19 07:14:15
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pharm
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n304 quiz 2
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  1. aminoglycosides prototype?
    gentamicin
  2. aminoglycosides (gentamicin) side fx
    ototoxicity, nephrotoxicity
  3. aminoglycosides (gentamicin) administration
    • IV or IM
    • not absorbed well orally
  4. aminoglycosides (gentamicin) treats what types of bacteria
    gram - rods
  5. macrolide abx - prototype?
    erythromycin
  6. macrolides (erythromycin) used as alternate when?
    allergies to PCN
  7. macrolides (erythromycin) - therapeutic use?
    against gram (+) bacteria
  8. macrolides (erythromycin) side fx
    mostly GI upset.  possible QT prolongation
  9. clindamycin side fx
    • diarrhea
    • can lead to colitis
  10. clindamycin uses
    • systemic infections
    • by anaerobic bacteria
  11. penicillin AE?
    allergic reaction
  12. PCN targets?
    • effective against gram + and -
    • moreso against G+
  13. PCN route of administration?
    • not given PO.
    • IM or IV
  14. greatest risk of allergy?
    • PCN
    • within first 30 min
  15. cephalosporin prototype
    cefazolin
  16. cephalosporin mech of action?
    • cell wall inhibitor.
    • related to PCNs
  17. cephalosporin AE
    • GI upset
    • possible allergic reaction
    • possible colitis
  18. fluroquinolones mech of action?
    only class of abx to directly inhibit DNA synthesis of bacteria
  19. fluroquinolones adverse effects?
    • phototoxicity
    • pediatric warning.
    • CNS and tendon toxicity
  20. fluroquinolones primary use
    • GU infections
    • other G-, some G+
  21. metrodiazole (Flagyl) indications
    • C diff
    • derm infections (rosacea, acne)
  22. metrodiazole (Flagyl) - other than bacteria, effective against?
    protozoa
  23. sulfonamide AE?
    • stevens-johnsons syndrome
    • anemia
    • renal
  24. sulfonamide primary use?
    • UTIs
    • ulcerative colitis
    • cpnjunctivitis
  25. sulfonamide mech of action, target?
    • "starves" the cell of folate
    • broad spectrum (bacteria, protozoa, fungal)
  26. firstline categories for PUD?
    antibiotics, H2 receptor antagonists, PPI's
  27. H2 receptor agonists?
    reduce amount of gastric secretion
  28. PPI's 
    • reduce gastric acid
    • take before meals
  29. sucralfate
    • "mends" the lesions of PUD. 
    • GI protectant
  30. antacids
    • tums
    • neutralzie pH of stomach
  31. antacids nursing implications
    • take after meals
    • take hours after other meds
    • stool may turn black from bismuth
  32. effects/action of laxatives
    • stimulate motility
    • increase water and electrolytes at colon
  33. antidiarrheals mech of action
    slows motility
  34. antidiarrheals contraindications
    • diarrhea due to infection
    • underage of 2
    • taking MAO inhibitors
    • obstructive jaundice

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