NCTI- Pharmacology- Drug List B- Diazepam

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Author:
RunNickMarini
ID:
18445
Filename:
NCTI- Pharmacology- Drug List B- Diazepam
Updated:
2010-05-09 12:48:27
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NCTI Pharmacology Drug List Diazepam
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NCTI- Pharmacology- Drug List B- Diazepam
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  1. Diazepam
    trade name
    Valium
  2. Diazepam
    class
    • Anticonvulsant
    • Benzodiazepine
    • sedative-hypnotic
    • anti-anxiety (anxiolytic)
  3. Diazepam
    mechanism of action
    • Suppresses the spread of seizure activity and raises the seizure threshold in the motor cortex
    • Sedative effects depress the CNS and reduce anxiety
    • Skeletal muscle relaxant
    • Induces amnesia
  4. Diazepam
    indications
    • Generalized seizure activity and status epilepticus
    • Sedation prior to cardioversion or pacing of a conscious patient
    • Acute anxiety
    • Muscle relaxer
    • Chemical restraint
  5. Diazepam
    contraindications
    • Head injury/CNS Depression
    • Respiratory depression
    • Hypotension / depressed vital signs
    • Shock
    • Infants < 30 days old
  6. Diazepam
    side effects
    • Cardiovascular: bradycardia, hypotension, rebound tachycardia
    • Neurological: dizziness, drowsiness, headache
    • Respiratory: respiratory depression/arrest
    • Gastrointestinal: nausea/vomiting
  7. Diazepam
    precautions
    Use with caution in the elderly and very ill patients due to paradoxical effects
  8. Diazepam
    interactions
    Use with caution when patient is taking antihistamines, antidepressants, alcohol, narcotics, barbiturates, sedatives and hypnotics as these drug classifications may potentiate the effects
  9. Diazepam
    routes
    IV, IO, IM, PR
  10. Diazepam
    onset and duration
    Onset in 5 minutes with an unknown duration
  11. Diazepam
    dosages
    • Adult:
    • Seizures: 5-10 mg IV/IM. May repeat every 5-15 minutes prn to maximum dose of 20 mg
    • Anxiety: 5-10 mg IV/IMCardioversion: 5-10 mg IV titrated to effect

    Pediatric: 0.1 mg/kg IV/PR. May repeat every 5-15 minutes prn to maximum dose of 20 mg
  12. Diazepam
    notes
    not in riverside

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