NCTI- Pharmacology- Drug List B- Midazolam

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Author:
RunNickMarini
ID:
18446
Filename:
NCTI- Pharmacology- Drug List B- Midazolam
Updated:
2010-05-09 12:54:11
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NCTI Pharmacology Drug List Midazolam
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NCTI- Pharmacology- Drug List B- Midazolam
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  1. Midazolam
    trade name
    Versed
  2. Midazolam
    class
    • Amnesic Agent
    • Sedative/hypnotic
    • Anticonvulsant
    • Benzodiazepine
    • Tranquilizer
    • Anti-anxiety (anxiolytic)
  3. Midazolam
    mechanism of action
    • Reduces anxiety
    • Relaxes skeletal muscles
    • Produces short term CNS depression and amnesia
  4. Midazolam
    indications
    • Seizures
    • Premedication for synchronized cardioversion/TCP
    • One of the premeditations for RSI
  5. Midazolam
    contraindications
    • Acute narrow-angle glaucoma
    • Shock (from hypovolemia)
    • Hypotension (from hypovolemia)
    • Alcohol or drug intoxication
    • Allergies to cherries
  6. Midazolam
    side effects
    • Cardiovascular: bradycardia, rebound tachycardia, hypotension
    • Neurological: amnesia, drowsiness, agitation, ALOC
    • Respiratory: respiratory depression or arrestG
    • astrointestinal: nausea/vomiting
  7. Midazolam
    precautions
    • Elderly patients with impaired respiratory function
    • Patients with renal failure, liver failure or COPD
  8. Midazolam
    interactions
    Other CNS depressants or benzodiazepines
  9. Midazolam
    routes
    IV, IO, IM, IN
  10. Midazolam
    onset and duration
    Onset in 1-5 minutes (IV/IO/IN) or 5-15 (IM) and may last 2-6 hours
  11. Midazolam
    dosages
    • Adult:
    • Pre-cardioversion or transcutaneous pacing: – 2.5 mg slow IV/IO
    • Seizure: 0.1 mg/kg slow IV/IO/IN or 0.2 mg/kg IM to a maximum of 5.0 mg

    Pediatric: Seizure: 0.1 mg/kg slow IV/IO/IN or 0.2 mg/kg IM to a maximum of 5.0 mg
  12. Midazolam
    notes
    none

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