Pulmonary

Card Set Information

Author:
sini
ID:
184880
Filename:
Pulmonary
Updated:
2012-11-21 22:53:05
Tags:
Asthma Medications
Folders:

Description:
Asthma Medications
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  1. Rapid acting beta2-agonist
    - Names
    - MOA
    - Use
    • Names: albuterol; pirbuterol; bitolterol
    • MOA: bronchodilators that relax airway smooth muscle; rapid onset of action
    • Use: first line of therapy in mild intermittent cases; during exacerbations
  2. Long-acting beta2-agonist
    - Names
    - MOA
    - Use
    • Names: salmeterol; formoterol; sustained-release albuterol
    • MOA: Bronchodilators that relax airway smooth muscle; gradual onset; sustained activity
    • Use: regular use for moderate persistent or severe asthma
  3. Inhaled corticosteroids
    - Names
    - MOA
    - Uses
    • Names: beclomethasone; flunisolide
    • MOA: decrease number and activity of cells involved in airway inflammation
    • Uses: mild persistent or worse cases; frequently combined with beta2 agonist use
  4. Leukotriene inhibitors
    - Names
    - MOA
    - Uses
    • Names: zafirlukast; zileuton
    • MOA: block activity or production of leukotrienes that are involved in inflammation and bronchospasm
    • Uses: oral agents; adjunctive therapy in mild persistent or worse cases
  5. Mast cell stabilizing agents
    - Names
    - MOA
    - Uses
    • Names: cromolyn; nedocromil
    • MOA: stabilizes mast cells; anti-inflammatory prophylaxis
    • Uses: NOT useful acutely; anti-inflammatory prophylaxis in mild persistent cases
  6. Theophylline
    - MOA
    - Uses
     
    • MOA: bronchodilator
    • Uses: useful as adjunct in mild persistent or worse cases (no longer 1st line of therapy)
  7. Anticholinergic agents
    - Names
    - MOA
    - Uses
    • Names: ipratropum
    • MOA: blocks vagal-mediated smooth muscle contraction
    • Uses: adjunctive therapy in moderate to severe cases
  8. Systemic steroids
    - Names
    - MOA
    - Uses
    • Names: methylprednisolone; prednisone
    • MOA: decrease number and activity of of cells involved in ariwary inflammation
    • Uses: adjunctive therapy in severe refractory cases

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