Amyotrophic Lateral Sclerosis (ALS)
Lou Gehrig’s disease – neuromuscular condition involving destruction of anterior horn motor neurons and fibers of the pyramidal tract
Symptoms – loss of the ability to speak, swallow, and breathe, as well as walk & use arms/hands
Death occurs within five years
Linked to malfunctioning genes for glutamate transporter and/or superoxide dismutase - involved in protection of neuron health.