NCTI- Pharmacology- Drug List C- Sodium Bicarbonate

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RunNickMarini
ID:
18562
Filename:
NCTI- Pharmacology- Drug List C- Sodium Bicarbonate
Updated:
2010-05-09 23:36:18
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NCTI Pharmacology Drug List Sodium Bicarbonate
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NCTI- Pharmacology- Drug List C- Sodium Bicarbonate
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  1. Sodium Bicarbonate
    trade name
    NaHCO3
  2. Sodium Bicarbonate
    class
    Alkalinizing Agent
  3. Sodium Bicarbonate
    mechanism of action
    • Increases blood pH by neutralizing excess buildup of acids
    • Decreases precipitation of myoglobin in renal tubules
  4. Sodium Bicarbonate
    indications
    • Cardiopulmonary Arrest with:
    • unsuccessful drug therapy and defibrillation
    • suspected tricyclic overdose (acidosis)
    • suspected hyperkalemia (elevated potassium in dialysis patients)

    Crush syndrome or crush injury greater than 4 hours
  5. Sodium Bicarbonate
    contraindications
    none
  6. Sodium Bicarbonate
    side effects
    • Neurological: headache, confusion, tetany (intermittent tonic spasms), seizures
    • Respiratory: pulmonary edema
    • Other: metabolic alkalosis, hypokalemia, hypocalcemia, tissue acidosis
  7. Sodium Bicarbonate
    precautions
    • Use with caution in patients with CHF
    • Administer for crush syndrome prior to removal of entrapped patient
  8. Sodium Bicarbonate
    interactions
    Flush IV before and after administration as it will precipitate with calcium chloride and inactivates catecholamines
  9. Sodium Bicarbonate
    routes
    IV, IO
  10. Sodium Bicarbonate
    onset and duration
    Onset is immediate and may last 1-2 hours
  11. Sodium Bicarbonate
    dosages
    • Adult: 1 mEq/kg IV/IO
    • Pediatric: 1 mEq/kg IV/IO
  12. Sodium Bicarbonate
    notes
    Verify IV patency before administration as it will cause tissue necrosis

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