NCTI- Pharmacology- Drug List C- Calcium Chloride

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  1. Calcium Chloride
    trade name
  2. Calcium Chloride
  3. Calcium Chloride
    mechanism of action
    • Necessary for the proper function of the nervous, muscular, skeletal, digestive and endocrine systems
    • Positive inotropic activity increases the strength of the myocardial contractions
    • increases ventricular automaticity
  4. Calcium Chloride
    • Calcium Channel Blocker or Beta blocker overdose
    • Acute hyperkalemia or cardiac arrest when hyperkalemia is suspected
    • Hypocalcemia
    • Suspected hypermagnesemia
  5. Calcium Chloride
    • Digitalis toxicity
    • Hypercalcemia
    • Ventricular fibrillation
  6. Calcium Chloride
    side effects
    • Cardiovascular: hypotension, dysrhythmias, cardiac arrest
    • Neurological: syncope, tingling sensations
    • Gastrointestinal: metallic taste
    • Other: sense of heat waves, necrosis/cellulitis upon infiltration of IV
  7. Calcium Chloride
    • Use with caution in patients with renal insufficiency or history of cardiac disease
    • May cause cerebral or coronary vasospasm
    • Can cause bradycardia if administration is too rapid
    • Safe use in children, pregnant mothers or nursing mothers has not been established.
  8. Calcium Chloride
    • Do not mix with sodium bicarbonate (forms precipitate crystals in blood)
    • Potentiates the effects of digitalis
    • Antagonizes the effects of calcium channel blockers
  9. Calcium Chloride
    IV, IO push
  10. Calcium Chloride
    onset and duration
    Onset is immediate with an unknown duration
  11. Calcium Chloride
    • Adult:
    • Known or suspected hyperkalemia or Beta Blocker OD: 500-1000 mg slow IV/IO (may repeat in10 minutes). Max single dose 1 gram
    • Calcium channel blocker (prophylaxis):2-4 mg/kg

    Pediatric: 20 mg/kg (0.2ml/kg) slow IV/IO

    Riverside County: not included in the Riverside County protocol
  12. Calcium Chloride
    Always flush IV after administration of any drug, in particular those that could form a precipitate like sodium bicarbonate.
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NCTI- Pharmacology- Drug List C- Calcium Chloride
NCTI- Pharmacology- Drug List C- Calcium Chloride
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