NCTI- Pharmacology- Drug List C- Lidocaine Hydrochloride

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RunNickMarini
ID:
18571
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NCTI- Pharmacology- Drug List C- Lidocaine Hydrochloride
Updated:
2010-05-09 23:55:47
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NCTI Pharmacology Drug List Lidocaine Hydrochloride
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NCTI- Pharmacology- Drug List C- Lidocaine Hydrochloride
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  1. Lidocaine Hydrochloride
    trade name
    • Xylocaine
    • Xylocard
  2. Lidocaine Hydrochloride
    class
    • Antidysrhythmic Agent
    • Local Anesthetic
  3. Lidocaine Hydrochloride
    mechanism of action
    • Suppresses ventricular ectopy
    • Increases ventricular fibrillation threshold
    • Decreases speed of electrical impulse through the conduction system
  4. Lidocaine Hydrochloride
    indications
    • Ventricular dysrhythmias: symptomatic PVCs and VTach
    • Cardiac arrest: VFib/pulseless VTach
    • Post conversion from a ventricular dysrhythmia (with pulses or pulseless) into a perfusing rhythm
  5. Lidocaine Hydrochloride
    contraindications
    • Second degree heart block, Mobitz II
    • Third degree heart block
    • Junctional bradycardia
    • Ventricular ectopy associated with bradycardia
    • Idioventricular rhythm
  6. Lidocaine Hydrochloride
    side effects
    • Cardiovascular: bradycardia, hypotension, arrest
    • Neurological: paresthesia, disorientation, slurred speech, seizures, lightheadedness, muscle twitching, tinnitis, blurred vision
    • Respiratory: dyspnea, depression, apnea
  7. Lidocaine Hydrochloride
    precautions
    Due to reduced ability to excrete the drug and the resulting accumulation of the drug in the body, reduce dose in: suspected liver disease, suspected kidney disease, cardiogenic shock, pulmonary edema and the elderly
  8. Lidocaine Hydrochloride
    interactions
    • Increased effects in patients taking beta blockers, cimetidine (Tagamet), quinidine, and phenytoin (Dilantin)
    • Decreases effects when mixed with barbiturates
  9. Lidocaine Hydrochloride
    routes
    IVP, IO, IVPB, ET
  10. Lidocaine Hydrochloride
    onset and duration
    Onset in 1-3 minutes and may last 10-20 minutes
  11. Lidocaine Hydrochloride
    dosages
    • Adult:
    • VFib/Pulseless VTach: 1.0-1.5 mg/kg slow IVP/IO (over 1 minute) or 3 mg/kg ET. May repeat 1.5 mg/kg IVP/IO once (no repeat for ET). Maximum dose of 3 mg/kg

    Ventricular Ectopy/Post Conversion:1 mg/kg slow IVP/IO (50 mg/minute) or 2 mg/kg ET. May repeat 0.5 mg/kg slow IVP/IO (50 mg/minute) every 5-10 minutes to a maximum of 3 mg/kg. May repeat 1 mg/kg ET once


    • Pediatric:
    • VFib/Pulseless VTach:1 mg/kg slow IVP/IO (over 1 minute) or 2 mg/kg ET. May repeat 1 mg/kg IVP/IO every 3-5 minutes or 1 mg/kg ET. Maximum dose of 3 mg/kg

    Ventricular Ectopy/Post Conversion:1 mg/kg slow IVP/IO (50 mg/minute) or 2 mg/kg ET. May repeat 1 mg/kg slow IVP/IO (50 mg/minute) or 1 mg/kg ET Maximum dose of 3 mg/kg
  12. Lidocaine Hydrochloride
    notes
    Signs of Lidocaine Toxicity: vision disturbances (blurred or double vision), tinnitus, trembling, dyspnea, dizziness/syncope, seizures, chest pain, palpitations and bradycardic dysrhythmias

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