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What is Hematocrit?
The % of RBCs in a sample of whole blood
What is the buffy coat?
A layer of WBCs btwn the heavier RBC layer and lighter plasma
What is anemia?
- Deficient levels of O2 in blood.
- Decreased capacity to carry O2/CO2
What are the 5 types of anemia and what are they caused by?
Iron deficiency anemia - inability to produce hemoglobin due to low iron levels (heme contains an atom of Fe)
Aplastic anemia - bone marrow cannot produce adequate RBCs
Pernicious anemia - lack of Vitamin B12 necessary for cell division
Sickle cell anemia - incorrect folding of hemoglobin
Hemorrhagic anemia - rapid loss of blood
What is Polycythemia and what are some reasons this may occur?
Overproduction of RBCs; significant increase in RBCs
Living at high altitudes, strenuous athletic activity, tumors in bone marrow
What is Erythrocyte Sedimentation Rate?
Measurement of the settling of RBCs in a vertical, stationary tube of blood during 1 hour
What are each of these called and what % are they found in humans? (on average)
- 1 - plasma 54-55%
- 2 - buffy coat (WBCs + platelets) < 1%
- 3 - RBCs 45%
What % of BW is blood?
What os the normal pH of blood?
7.35 - 7.45
What is the composition of blood?
- Plasma (proteins, enz's, electrolytes, etc...)
- Cells (RBCs, WBCs, platlets)
What are the 3 types of cells in blood (scientific names), and what is their function?
- Erythrocytes - carry O2/CO2
- Leukocytes - immune defense
- Thrombocytes - clotting
What is the function of plasma?
Nutrition, transportation, osmotic pressure, acid/alkaline balance
What are the different blood types, their antigens, and antibodies?