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What are the two major components of connective tissue?
Extracellular matrix and cells
What are the five major fuctions of connective tissue?
- Defense: physical (via hyaluronic acid) and Immunological
- Storage (water, electrolites and lipids)
- Transport (except in CNS)
What are the major components of the matrix?
What forms the ground substance?
- hyaluronic acid
What are the three types of fibers?
- Collagen fibers
- reticular fibers
- elastic fibers
What are the most common fibers that form oth tropocollagens?
Types I, II, III
What is the purpose of collagen fibers?
add strength to connective tissue
What is the dominant type of fiber found in tendons, ligaments, organ coverings, facia?
What type of fibers are delicate and form fine networks?
What type of fiber in the main fiber found in visceral organs (i.e., liver, kidney, spleen)?
What type of fibers are found in artery, veins, and ligamentum flavum?
What are the two main classifications for connective tissue cells?
- Fixed cells
- wandering cells
What is the most common type of connective tissue cells (true cells)?
What are the inactive and active forms of fibrocytes?
- Inactive = fibrocyte
- Active = fibroblast (repair tissue)
What type of cells is an adipocyte?
What type of connective tissue cells originate in the bone marrow and migrate through the blood?
What are the main types of wandering cells?
- mast cells
- plasma cells
- reticual cells
What are the most prominant substances found in mast cells?
What type of wandering cell can differentiate into plasma cells?
What disease is caused by a lack of collagen which causes blood capillaries to hemorrhage?
What is the main functioin of fibrocytes and fibroblasts?
repair damaged tissue
Where is elastic tissue found?
dermis, walls of veins and arteries
What is the orientation of dense irregular and dense regular connective tissue?
- Irregular = no clear orientation, densley woven 3D network
- Regular = run parallel (tendons and ligaments)
What are the characteristics of loose connective tissue?
- cell rich
- rich in vessels and nerves