N. fowferi- Primary Amebic Meningoencephalitis (PAM)
An acute suppurative infection of the brain and meninges that is rapidly fatal and usually diagnosed ante-mortum.
Primary Amebic Meningoencephalitis (PAM)
Caused by Naegleria spp.
AmpB (not really effective)
GAE/PAM: Which one is a more slowly progressive, chronic disease associated with environmental exposures?
Acanthamoeba or Leptomyxic amebae
GAE/PAM: cysts with wrinkled-walls
Ring inflitrate of cornea (yellow eye)
Definitive hosts of Toxoplasma gondii
cats (family Felidae)
What stage of Toxoplasma gondii forms the reservoirs fo infective tissue cysts?
Non-motile bradyzoite stage
What stage of Toxoplasma gondii exhibits asexual reproduction?
Motil tachyzoite disease producing stage
+ IgM titer in serum of newborn
Asymptomatic Congenital Toxo (ACT)
Disseminated infection may exist in AIDS pts w/o demonstrable titer
Serologic Diagnosis of Toxo-1
Fungus causing significant opportunistic infections in immunosuppressed/immunocompromised patients, most common life threatening infection of AIDS patients in US before HAART (Highly Active Anti-Retroviral Therapy)
Pneumocystic (carinii) jirovecii
Thickened alveolar wwalls and alveoli filled with "foamy" eosinophilic exudate