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DesLee26
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a. Why is it dominant?
i. Alleles are simply variations in __
1. When dominant coexists with recessive in heterozygote, they don’t interact
a. It is in the __that come into play
- Dominant because it’s seen phenotype, not because subdues recessive allele
- gene’s nucleotide sequence
- pathway from genotype to phenotype
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b. For any character, the observed dominant/ recessive relationship of alleles depends on level of phenotype examination:
Ex:
i. Tay-Sachs
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i. Tay-Sachs
1. Brain cells of kid cannot __ due to malfunctioned crucial enzyme
a. Lipids accumulate in __-->__-->__--> degeneration of motor and mental performance
- metabolize certain lipids
- brain
- seizures
- blindness
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2. Only kids who inherit two copies of __ have it
a. At organismal level: __
b. Activity level of lipid-metabolizing enzyme is __between for heterozygous
i. Biochemical level: __
c. Molecular level: normal allele and Tay-Sachs allele are __
i. Equal numbers of normal and dysfunctional enzyme molecules
- Tay-Sachs allele
- recessive
- intermediate
- incomplete dominance
- codominant
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True or False: Dominant Alleles are always more popular than recessive gene
False not
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c. Multiple Alleles
i. Most genes occur in more than __allelic forms
1. ABO blood groups: __alleles
a. Blood group (__) may be one of four types
i. A and B refer to two __on surface of RBCs
ii. Neither is O
- two
- three
- phenotype
- carbohydrates
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d. Pleiotrophy
i. Most genes have multiple phenotypic effects= __
1. Responsible for multiple symptoms associated with certain hereditary diseases
pleiotrophy
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