Biochem Phospholipids, Cholesterol, lipoproteins, steroid hormones

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Author:
bradley.knox
ID:
188199
Filename:
Biochem Phospholipids, Cholesterol, lipoproteins, steroid hormones
Updated:
2012-12-09 16:38:04
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biochem
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biochem
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  1. What has the structure of a DAG with a phosphate on carbon 3?
    Glycerophospholipids AKA phosphoglycerides
  2. What are the four main functions of glycerophospholipids?
    • Cell membrane component
    • intracellular messengers
    • Anchors proteins to cell membranes
    • Lung surfactant (prevents alveoli from collapsing)
  3. What are the two types of phosphoglycerides?
    • Plasmalogen
    • Plate-activating factor
  4. What is the backbone of sphingolipids aka sphingomyelin?
    Sphingosine (amino acid)
  5. What originates from unsaturated fatty acids with 20 caarbons?
    Eicosanoids
  6. How do eicosanoids differ from hormones?
    • 1. they are made in small amounts in all tissues
    • 2. act locally, not transported like hormones
    • 3. Not stored
    • 4. G-protein mechanism
  7. Leukotrines = ?
    inflammation
  8. What enzyme is present in most tissues and contributes to the health of gastric tissues?
    COX-1
  9. What enzyme is present in fewer tissues and are part of the immune/inflamatory response?
    COX-2
  10. What acts as the structural component of all membranes and is the precursor to bile acids, steroid hormones, and vitamin D?
    Cholesterol
  11. What is the regulatory enzyme in cholesterol synthesis?
    HMG CoA reductase
  12. Where does cholesterol synthesis occur?
    Cytoplasm
  13. What is needed for cholesterol synthesis?
    • NADPH
    • Acetyl CoA and ATP
  14. What does A Happy Man Is Singing Carols stand for?
    • Acetyl CoA
    • HMG CoA
    • Mevalonate
    • Isoprene
    • Squalene
    • Cholesterol
  15. What is a spherical macromolecular complexes of lipid and protein?
    Lipoproteins
  16. What is the main function of Lipoproteins?
    Keep lipids soluble and transport them to plasma
  17. What are TAGs transported from intestine to other tissues?
    chylomicrons
  18. Tags transported to fat tissue
    VLDL
  19. Cholesterol transported to peripheral tissues?
    LDL
  20. Cholesterol to liver
    HDL
  21. what do steroid hormones always start with?
    Cholesterol
  22. What are the first three steps in steroid synthesis?
    Cholesterol => pregnenolone => Progesterone
  23. What is the parent compound of all steroid hormones?
    Pregnenolone or progesterone

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