drug lit stats

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188592
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drug lit stats
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2012-12-10 20:03:20
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drug lit stats
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  1. what determines statistical significance
    alpha
  2. what determines clinical significance
    delta
  3. variable that is being manipulated
    factors or treatments
    independent
  4. variable that is the outcome
    dependent
  5. PICO
    • problem
    • intervention
    • comparison
    • outcome
  6. intervention plus comparison is what
    independent variable
  7. discrete data
    • nominal and ordinal
    • lists/tables
  8. continuous data
    • interval and ratios
    • graphs
  9. male - female
    nominal
  10. difference between the poisson and the binomial distribution
    binomial - all eligibe phenomena are studied

    poisson - only the cases with a particular outcome are studied
  11. scale - severity (pain scale)
    ordinal
  12. constant and defined units of measurement
    scale that can cross 0. -20-----20
    temperature
    interval
  13. scale that doesn't cross the O. 0-----32
    if zero - then dead
    ratio
  14. normal curve tests
    parametric
  15. test of non-normal curve
    nonparametric
  16. when is a fisher's exact test used
    if the expected value is less than 5
  17. which scales have a SD
    interval and ratio
  18. standard deviation expressed as percentage of the mean
    useful to compare the relative differences between two or more samples
    coefficient of variation
  19. the statistics found that the null hypothesis is false when it is really true
    type I or alpha
  20. the statistics found the null hypothesis is true when it is really false
    type II or beta
  21. what is the P in PICO studing
    the population at risk
  22. predetermined largest probability of a false non-rejection of the null the researchers are willing to accept
    • beta
    • the smaller selected the larger the sample size that is needed
  23. probability that a difference will be detected and the null hypothesis will be rejected when it should be rejected
    power
  24. what is power usually
    80%
  25. what does power depend on
    • sample size
    • alpha level
    • delta
  26. what is beta usually
    20%
  27. determine how much of a change want to see
    • effect size
    • delta
  28. range of values that has a specified probability of containing the parameter being estimated
    confidence interval
  29. 3 SEM
    99%
  30. 2 SEM
    95%
  31. 1 SEM
    68%
  32. how many times more likely an outcome is in one group compared to the other
    risk ratio
  33. odds of an outcome in one group compared to the odds of the outcome in the other group
    odds ratio
  34. the probability that a healthy person will develop A disease in a specified period
    incidence
  35. the number of cases at a specific time
    prevalence

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