Infectious Disease Therapeutics

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azbenchaar
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188954
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Infectious Disease Therapeutics
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2012-12-12 02:08:58
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Infectious Disease Therapeutics
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Infectious Disease Therapeutics
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  1. Staphylococcus aureus
    Aerobic Gram-Positive Cocci (AGPC)

    (Skin flora, Hospital and community-acquired pneumonia, SSTIs, osteomyelitis, endocarditis, septic arthritis, blood and catheter infections, MSSA/MRSA)
  2. Staphylococcus epidermidis
    Aerobic Gram-Positive Cocci (AGPC)

    (aka Coagulase-negative Staphylococcus epidermidis, CoNS)

    (Skin flora. Foley (urine) catheter and IV line infections, prosthetic device infections, contaminates blood cultures)

    (More likely to be a contaminant, and NOT a true pathogen.)
  3. Staphylococcus saprophyticus
    Aerobic Gram-Positive Cocci (AGPC)

    (Vaginal flora. UTIs: 2nd to E. coli in younger, sexually active females)
  4. Streptococcus pyogenes
    Aerobic Gram-Positive Cocci (AGPC)

    (Grp A β-hemolytic)

    (Skin flora. Strep throat (pharyngitis), SSTIs, scarlet fever, rheumatic fever, glomerulonephritis)

    (Pyogenes = pus formation/production.)
  5. Streptococcus agalactiae
    Aerobic Gram-Positive Cocci (AGPC)

    (Grp B β-hemolytic)

    (Vaginal flora. Neonatal meningitis, pneumonia, and sepsis)

    (Group B, "B for baby")
  6. Streptococcus pneumoniae
    Aerobic Gram-Positive Cocci (AGPC)

    (α-hemolytic)

    (Community-acquired pneumonia (CAP), otitis media, bacterial meningitis)

    • (Common association with dental caries.)
    • (If you have an abcess or some source of S. pneumoniae, you should check Pt's teeth since this may be the orignal source.)
  7. Viridans Group Streptococci

    (S. anginosus (aka S. milleri), S. mutans, S. mitis,
    S. salivarius, S. sanguis, Gamella morbillorum)
    Aerobic Gram-Positive Cocci (AGPC)

    (α-hemolytic)

    (GI flora. Dental infections, endocarditis, abscesses)
  8. Streptococcus bovis
    Aerobic Gram-Positive Cocci (AGPC)

    (Grp D Nonenterococcal Strep.)

    (GI flora. Associated with colon cancer)
  9. Enterococcus faecalis
    Aerobic Gram-Positive Cocci (AGPC)

    (GI flora. UTIs, biliary infections, bacteremia, endocarditis, VRE)

    (Usually treated with ampicillin or a very broad penicillin.  Since the Tx is different than for streptococcus it is classified as enterococcus, otherwise it would have been classified as strep. since it is very similar (strep. is usually treated with penicillin or cephalosporins))
  10. Enterococcus faecium
    Aerobic Gram-Positive Cocci (AGPC)

    (GI flora. UTIs, biliary infections, bacteremia, endocarditis, VRE)

    (Usually treated with ampicillin or a very broad penicillin. Since the Tx is different than for streptococcus it is classified as enterococcus, otherwise it would have been classified as strep. since it is very similar (strep. is usually treated with penicillin or cephalosporins))
  11. Clostridium perfringens
    Aerobic Gram-Positive Bacilli (AGPB)

    SPORE-FORMING

    (Gas Gangrene  - cellulitis/wound infections)
  12. Clostridium difficile
    Aerobic Gram-Positive Bacilli (AGPB)

    SPORE-FORMING

    (Antibiotic-induced diarrhea, Pseudomembraneous enterocolitis)
  13. Actinomyces spp.
    Aerobic Gram-Positive Bacilli (AGPB)

    NON-SPORE-FORMING
  14. Propionibacterium acnes
    Aerobic Gram-Positive Bacilli (AGPB)

    NON-SPORE-FORMING
  15. Lactobacillus spp.
    Aerobic Gram-Positive Bacilli (AGPB)

    NON-SPORE-FORMING
  16. Peptostreptococcus spp.
    Anaerobic Gram-Positive Cocci (AN-GPC)

    (GI/vaginal/mouth flora. Abscesses, aspiration pneumonia)
  17. Peptococcus spp.
    Anaerobic Gram-Positive Cocci (AN-GPC)

    (GI/vaginal/mouth flora. Abscesses, aspiration pneumonia)
  18. Chlamydia trachomatis
    Miscellaneous

    NO CELL WALL

    (STD)

    (Miscellaneous because they do NOT stain well, so you can't tell if they are G+ or G-.)
  19. Chlamydophilia pneumoniae

    (Formerly: chlamydia pneumoniae)
    Miscellaneous

    NO CELL WALL

    (Atypical organism. CAP)

    (Miscellaneous because they do NOT stain well, so you can't tell if they are G+ or G-.)
  20. Rickettsia rickettsii
    Miscellaneous

    (Rocky Mountain Spotted Fever)

    (Miscellaneous because they do NOT stain well, so you can't tell if they are G+ or G-.)
  21. Mycoplasma  pneumoniae
    Miscellaneous

    NO CELL WALL

    (Atypical organism. CAP)

    (Miscellaneous because they do NOT stain well, so you can't tell if they are G+ or G-.)
  22. Borrelia burgdorferi
    Miscellaneous

    (Lyme disease)

    (Miscellaneous because they do NOT stain well, so you can't tell if they are G+ or G-.)
  23. Treponema pallidum
    Miscellaneous

    (Syphilis)

    (Miscellaneous because they do NOT stain well, so you can't tell if they are G+ or G-.)
  24. Mycobacterium tuberculosis
    Miscellaneous

    (This is tough one......tuberculosis)

    (Miscellaneous because they do NOT stain well, so you can't tell if they are G+ or G-.)
  25. Escherichia coli
    Aerobic Gram-Negative Bacilli (AGNB)

    Enterobacteriaceae (“enteric”)

    (Diarrhea, UTIs, neonatal meningitis, sepsis)
  26. Klebsiella spp.
    Aerobic Gram-Negative Bacilli (AGNB)

    Enterobacteriaceae (“enteric”)

    • (UTIs (foley catheters), nosocomial pneumonia, sepsis)
  27. Enterobacter spp.
    Aerobic Gram-Negative Bacilli (AGNB)

    Enterobacteriaceae (“enteric”)

    (Nosocomial infections)
  28. Citrobacter spp.
    Aerobic Gram-Negative Bacilli (AGNB)

    Enterobacteriaceae (“enteric”)

    (Nosocomial infections)
  29. Proteus mirabilis
    Aerobic Gram-Negative Bacilli (AGNB)

    Enterobacteriaceae (“enteric”)

    (UTIs, nosocomial infections)
  30. Providencia spp.
    Aerobic Gram-Negative Bacilli (AGNB)

    Enterobacteriaceae (“enteric”)
  31. Morganella morganii
    Aerobic Gram-Negative Bacilli (AGNB)

    Enterobacteriaceae (“enteric”)
  32. Serratia spp.
    Aerobic Gram-Negative Bacilli (AGNB)

    Enterobacteriaceae (“enteric”)

    (UTIs, wound infections, pneumonia)
  33. Shigella spp.
    Aerobic Gram-Negative Bacilli (AGNB)

    Enterobacteriaceae (“enteric”)

    (Dysentery. Not GI normal flora – pathogen)
  34. Salmonella spp.
    Aerobic Gram-Negative Bacilli (AGNB)

    Enterobacteriaceae (“enteric”)

    (Typhoid fever, diarrhea, sepsis, carrier)
  35. Yersinia enterocolitica
    Aerobic Gram-Negative Bacilli (AGNB)

    Enterobacteriaceae (“enteric”)

    • (Diarrhea)
  36. Pseudomonas aeruginosa
    Aerobic Gram-Negative Bacilli (AGNB)

    NON-enterobacteriaceae (Can easily develop resistance)

    (Nosocomial infections: pneumonia, osteomyelitis, sepsis, UTIs, endocarditis)
  37. Acinetobacter baumannii
    Aerobic Gram-Negative Bacilli (AGNB)

    NON-enterobacteriaceae (Can easily develop resistance)

    (Nosocomial infections)
  38. Stenotrophomonas (Xanthamonas) maltophilia
    Aerobic Gram-Negative Bacilli (AGNB)

    NON-enterobacteriaceae (Can easily develop resistance)

    (Nosocomial infections)
  39. Haemophilus influenzae
    Aerobic Gram-Negative Bacilli (AGNB)

    NON-enterobacteriaceae (Can easily develop resistance)

    (Influenzae, meningitis, epiglottitis, septic arthritis, sepsis)
  40. Legionella pneumophilia
    Aerobic Gram-Negative Bacilli (AGNB)

    NON-enterobacteriaceae (Can easily develop resistance)

    (CAP)

    (Atypical organism. Causes respiratory infections, BUT presents with viral-like Sx.)
  41. Bordetella pertussis
    Aerobic Gram-Negative Bacilli (AGNB)

    NON-enterobacteriaceae (Can easily develop resistance)

    (Whooping cough)
  42. Bartonella henselae
    Aerobic Gram-Negative Bacilli (AGNB)

    NON-enterobacteriaceae (Can easily develop resistance)

    (Cat scratch disease)
  43. Pasteurella multocida
    Aerobic Gram-Negative Bacilli (AGNB)

    NON-enterobacteriaceae (Can easily develop resistance)

    (Animal bites/scratches)
  44. Helicobacter pylori (H. pylori)
    Aerobic Gram-Negative Bacilli (AGNB)

    NON-enterobacteriaceae (Can easily develop resistance)

    (GI ulcers, gastritis)
  45. Brucella spp.
    Aerobic Gram-Negative Bacilli (AGNB)

    NON-enterobacteriaceae (Can easily develop resistance)

    (Undulant fevers)
  46. Vibrio cholera
    Aerobic Gram-Negative Bacilli (AGNB)

    NON-enterobacteriaceae (Can easily develop resistance)

    (Diarrhea)
  47. Campylobacter jejuni
    Aerobic Gram-Negative Bacilli (AGNB)

    NON-enterobacteriaceae (Can easily develop resistance)

    (Diarrhea)
  48. Neisseria meningitidis
    Aerobic Gram-Negative Cocci (AGNC)

    (Meningitis (<1 yo), sepsis)
  49. Neisseria gonorrhoeae
    Aerobic Gram-Negative Cocci (AGNC)

    (STD - gonorrhea, septic arthritis)
  50. Moraxella catarrhalis
    Aerobic Gram-Negative Cocci (AGNC)

    (Respiratory infections, CAP)
  51. Bacteroides fragilis
    Anaerobic Gram-Negative Bacilli (AN-GNB)

    (GI/vaginal flora. Abscesses)
  52. Bacteroides melaninogenicus
    Anaerobic Gram-Negative Bacilli (AN-GNB)

    (GI/vaginal/mouth flora. Aspiration pneumonia, periodontal disease)
  53. Fusobacterium spp.
    Anaerobic Gram-Negative Bacilli (AN-GNB)

    (Aspiration pneumonia, periodontal diseases, abdominal/pelvic abscesses)
  54. Prevotella  spp.
    Anaerobic Gram-Negative Bacilli (AN-GNB)

    (Periodontal diseases)
  55. Veillonella spp.
    Anaerobic Gram-Negative Cocci (AN-GNC)

    (GI normal flora. Rare cases of osteomyelitis and endocarditis)

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