Home > Flashcards > Print Preview

The flashcards below were created by user stephjg on FreezingBlue Flashcards. What would you like to do?

  1. In the vas deferens, how many layers of smooth muscle are there?
    • 3 layers: long/circulatory/long
    • Involved in ejaculatory contraction
  2. Describe the epithelium and lamina propri of the vas deferens.
    • Epl: pseudostratified with basal cells and principal cells with stereocilia 
    • L. Propria:  Core of lamina propria makes the epl folded 
  3. How is the smooth muscle of the vas deferens controlled?
    • Contraction is initiated by sympathetic control
    • Short lived response
    • Powerful rhythmic contractions for active ejaculation of spermatazoa
  4. Where does a vasectomy occur and what are the consequences of this procedure?
    • Occurs at the ductus (vas) deference
    • no hormonal disruption
    • spermatazoa and ejaculate are still produced
    • Principal epl cells of epididymis and ductus deferens become very phagocytic
    • In a small minority, an immune response against spermatazoa is mounted in the wall
  5. Describe the epl/muscle of the ejaculatory ducts.
    • Epl: similar to epididymis- pseudostratifed with basal cells and principal cells
    • Muscle:  no smooth muscle in walls
  6. How do spermatazoa travel through the ejaculatory ducts?
    • Passive flow, driven by the contraction of the vas deferens
    • passes through prostate, delivers spermatazoa and seminal fluid to the urethra
  7. Name the accessory genital glands nd provide their secretory function.
    • Seminal vesicles- secrete fructose-rich seminal fluid (majority of semen volume), provides energy for sperm motility
    • Cowper's (bulbourethral) glands- secrete GAG/Sialic Acid-Rich fluid for lubrication
    • Prostate- Secretes protease/fibrolytic enzyme which liquifies semen
  8. Describe the structure of the prostate.
    • Parenchyma (functional): exocrine, compound tubuloalveolar gland
    • pseudostratified epl including columnar cells for differentiation/secretion and basal cells for proliferation/hyperplasia, both of which are testosterone-responsive
    • Stroma (supportive):  Dense irregular connective tissue + sympathetic-responsive smooth muscle
    • intermingled smooth muscle for sympathetic controlled contraction
  9. How is the prostate histologically stained?
    Stained using a Prostate Specific Antigen-specific stain which appears brown under LM
  10. Compare benign prostate hyperplasia and prostate carcinoma.
    • Benign:  increased epl proliferation, cells remain polarized, still testosterone dependent
    • Carcinoma (malignant):  increase epl proliferation, not polarized, no lumen (appears endocrine instead of exocrine), PSA is released into the stroma and fenestrated capillaries, testosterone-independent
  11. What is the functional role of the urethra?
    Common urine/semen passage
  12. Describe the epithelial transitions in the urethra.
    • Begins as transitional epl (expansion/contraction) in the prostatic urethra.  Then it becomes pseudostratified columnar epithelium (some mucous secretion) in the membranous/bulbar urethra.  Finally it becomes stratified squamous epl (protective, merges with skin externally) in the penile urethra.
    • Since the transition is gradual, there is a lower likelihood of tumour development, and it is protective of infection.
  13. Describe the structure of the penis.
    • Three columns of erectile tissue = corpora (corpus spongiosum and 2 corpora cavernosum)
    • Tissue of corpora is fibroelastic CT
    • Each corpus is surrounded by a dense irregular CT capsule (tunica albuginea)
    • Highly vascular- helicine arteries with prominent smooth muscle
    • Corpora contain venous spaces/sinuses
  14. Compare the flaccid and erect state of erectile tissue.
    • Flaccid state-
    • 1) helicine arterial smooth muscle contracted
    • 2) little blood to venous sinuses in corpora
    • 3) considerable blood shunted directly to non-corporal veins via arteriovenous anastomses (direct path from artery to vein without a capillary bed)
    • Erect state-
    • 1) Helicine arterial smooth muscle relaxed
    • 2)  Increased blood to venous sinuses which fill and expand
    • 3) Decreased drainage to veins from venous sinuses due to pressure against the tunica albuginea (maintains erection)
  15. Name the signals/messengers involved in facilitating erection.
    • Parasympathetic NS- relaxes helicine smooth muscle
    • Nitric oxide signalling- relaxes helicine smooth muscle
    • NO generated 2nd messenger, cGMP - facilitates filling of venous sinuses
  16. How does Viagra work?
    Viagra is a phosphodiesterase inhibitor which prevents the breakdown of cGMP to maintain filling of the venous sinuses

Card Set Information

2012-12-13 02:46:52
Male Reproductive System

ANAT390 Lecture 35 Male Reproductive System II
Show Answers:

What would you like to do?

Home > Flashcards > Print Preview