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alvo2234
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MOA of Elitek
- stimulates uridate oxidase
- increase excretion of allantoin
uridate oxidase -----> converts uric acid to allantoin
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Allopurinol MOA
- inhibits xanthine oxidase (xo)
- inhibits the biotransformation of azathioprine
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Benemid MOA
inhibits organic anion transporter (OAT)
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inhibition of TNF alpha
- simponi
- enbrel
- humira
- remicade
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inhibition of IL-1
anakinra, abatacept
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inhibition of production of IL-2
cyclosporine (all calcineurin inhibitors)
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inhibition of IMP
Cellcept
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inhibition of dihydrofolate reductase
MTX
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patient has RA and was given a prescription for a drug with a sig of 3 mg/kg/day at week 0,2,6
Remicade
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least likely to be experienced/exhibited by a pt who is taking Imuran for management of arthritis
leukocytosis
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Ms. Zoe has recalcitrant acne which has been managed with Sotret. WOTF is a least likely AE associated with that treatment regimen?
what are the AE associated with this medication?
- mood change
- suicidal ideations
- teratogenicity
- hypothyroidism
- night blindness
- muscoskeletal pain
- dryness of skin and eyes
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WOTF monoclonal antibodies produces a pharmacological effect by inhibition of IL-6
Tocilizumab (Actemra)
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Least likely to be an IND of Remicade
Bartters syndrome
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WOTF is least likely indicated for management of Rosacea
- Orencia (abatacept)
- Benzac wash (not effective against H. Pylori, which is involved in Rosacea
Benzac wash is used in acne bc it can open up pores
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signs and symptoms of rosacea
- gritty sensation in eyes
- telangiectasia
- red bulbous nose
- papules
- flushing
NO COMEDO IN ROSACEA
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allopurinol
zyloprim, aloprim
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azelaic acid
finacea, azelax
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