- Fluids & electrolytes:
- 1. low circulating volume & hemo-concentration
- 2. decreased cardiac output
- 3. depleted water-sol vitamins.
Increased ketone excretion increases water needs.
Change in fuel supply with reduced BMR: decrease in GNG, ketones become primary source of fuel, protein degradation is limited but not absent.
Protein breakdown initially enhanced, then slowed. No distinction between essential & nonessential!!!!!
Excess N is disposed of as urea.
Protein hydrolysis is major source of glucose during fasting. Death come when 1/3 of body protein is used.