Parasympathetic

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  1. Metacholine
    • MoA: ACh agonist
    • Use: Asthma diagnosis
    • Adverse Effect: Short 1/2 life
  2. Bethanechol
    • MoA: ACh agonist
    • Use: relax GI & urinary sm.
  3. Carbachol
    • MoA: ACh agonist
    • Use: relax GI & urinary sm.
  4. Pilocaprine
    • MoA: muscarinic ACh agonist
    • Use: Glaucoma, Xerostomia
  5. Cevimeline
    • MoA: muscarinic ACh agnoist
    • Use: Xerostomia
  6. Organophosphorus
    • MoA: Irreversible Anti-cholinesterase; bind esteratic site
    • Adverse effect: cause muascle paralysis
  7. Pralidoxime
    • MoA: bind anionic site on cholinesterase; reverse organosphosphorus
    • - Give with Atropine
  8. Edrophonium
    • MoA: short acting Anti-cholinesterase
    • Use: DIAGNOSIS of Myasthenia Gravis and NM blockers
  9. Neostigmine
    • MoA: anti-cholinesterase
    • Use: Myasthenia Gravis
    • Adverse Effect: cholinergic crisis when OD
  10. Physostigmine
    • MoA: anti-cholinesterase (CNS action)
    • Use: Galucoma, Atropine OD antidote
  11. Pyridostigmine
    • MoA: anti-cholinesterase
    • Use: Myasthenia Gravis, Nerve gas prevention
  12. Donepezil
    • MoA: anti-cholinesterase
    • Use: old Alzheimer's treatments
  13. Galantamine
    • MoA: anti-cholinesterase
    • Use: old Alzheimer's treatments
  14. Rivastigmine
    • MoA: anti-cholinesterase
    • Use: old Alzheimer's treatments
  15. Tacrine
    • MoA: anti-cholinesterase
    • Use: old Alzheimer's treatments
  16. Varenicline
    • MoA: ACh partial agonist
    • Use: competitive inhibitors for ACh over production
  17. Atropine
    • MoA: Anti-mACh receptors
    • Use: systemic parasympathetic inhibitions
  18. Scopolamine
    • MoA: Anti-ACh receptors
    • Use: treat motion sickness
  19. Dicyclomine
    • MoA: Anti-ACh receptors
    • Use: Anti-spasm
  20. Ipratropium
    • MoA: Anti-ACh receptors
    • Use: Bronchodilation (COPD, Asthma)
  21. Tiotropium
    • MoA: Anti-ACh receptors
    • Use: Bronchodilation (COPD, Asthma)
  22. Glycopyrrolate
    • MoA: Anti-ACh receptors
    • Use: inhibits bowl movement (pre-surgical use)
  23. Oxybutynin
    • MoA: Anti-ACh receptors
    • Use: treat overactive bladder
  24. Tolterodine
    • MoA: Anti-ACh receptors
    • Use: treat overactive bladder
  25. Darfienacin
    • MoA: Anti-ACh receptors
    • Use: treat overactive bladder
  26. Trihexyphyenidyl
    • MoA: Anti-ACh receptors (CNS action)
    • Use: Parkinson's treatment
  27. Benztropine
    • MoA: Anti-ACh receptors (CNS action)
    • Use: Parkinson's treatment
  28. Tricyclin Anti-depressant
    MoA: Anti-ACh receptors
  29. Antipsychotic agents
    MoA: Anti-ACh receptors
  30. H1 Histamine blocking agent
    MoA: Anti-ACh receptors
  31. Botulinum Toxin A
    • MoA: degrades SNAP-25 => prevent ACh release
    • Use: chronic migraine
    • Adverse effect: flaccid paralysis, respiratory paralysis
  32. Botulinum Toxin B
    • MoA: degrades VAMP/Synaptobrevin => prevent ACh release
    • Use: chronic migraine
    • Adverse effect: flaccid paralysis, respiratory paralysis

Card Set Information

Author:
xinchen3
ID:
189612
Filename:
Parasympathetic
Updated:
2012-12-15 17:27:07
Tags:
Parasympathetic
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Description:
Parasympathetic
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