Immuno

Card Set Information

Author:
Anonymous
ID:
19025
Filename:
Immuno
Updated:
2010-05-12 13:25:29
Tags:
USMLE
Folders:

Description:
from comlex book
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  1. Leukocyte adhesion deficiency
    CD18 - can't tightly bind and get out of blood stream.... no abscess and pus formation.... first sign umbilicus does not fall off
  2. Lymphoid signal
    IL-7
  3. Myeloid signal
    IL-3
  4. First antibody to be made
    IgM
  5. CD 19 and CD 21
    B cells
  6. CD 3
    T cells
  7. Substances chemoattractive to neutrophils
    IL-8 C5a fibriopeptides leukotriene B4 and formyl methionyl peptides
  8. phagocytosis enhanced by
    c3b
  9. Chronic granulomatous disease
    deficiency of NADPH oxidase - recurrent infection with cat + organisms
  10. inflammatory cytokines
    Il-1, Il-6 and TNF-alpha
  11. act as superantigens
    staph enterotoxins, TSST-1 and strep pyrogenic exotoxins
  12. Encourage TH1 reaction
    IL-12
  13. + feedback to continue TH1 response
    IFN-gamma (which also inhibits TH2 response
  14. Encourage TH2 response
    IL-4
  15. + feedback to continue TH2 response
    IL-4 (and inhibits TH1 response)

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