Toxicology

Card Set Information

Author:
Aulockhart
ID:
190989
Filename:
Toxicology
Updated:
2012-12-31 13:51:05
Tags:
OD toxicology Lead CN CO OTD
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Description:
Symptoms and Treatments for Drug overdoses
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  1. HA, Nausea, Dizzy, Confusion -> Tachycardia, Tachypnea, MI
    Carbon Monoxide
  2. Tx Carbon Monoxide 
    02 100% 220 -> 80. if, HBC -> 40
  3. HA, NV, Lethargy, Coma, HypoTN, Brady, Pulm edema, Ab pain, Seizures
    Cyanide

    • Hydroxoycobalamine (red MSU) Anaphylaxis Angioedema
    • NA Nitrate
    • NA Thiosulfate
    • Amyl Nitrate (also causes HA)
    •  *above three cause HyptoTN, and NV
  4. DUMBBELS -> Respiratory failure
    & Weakness -> Paralysis
    Organo phosphate

    • Isopto
    • protopam
  5. Encephalopathy (HA, seizure, coma, lethargy)
    GI (anorexia, constipation, ab pain)
    Peripheral NS (peripheral neuropathy, Foot drop)
    Lead

    • BAL - avoid if allergic to peanuts
    • ECD
    • Chemet
  6. NVD, Shock, delirium, lesions, pruritic diffuse rash, Hyper/o pigmentation, Mess linesHypoTN, death
    Arsenic

    • BAL
    • Chemet
  7. Hepatotoxic.

    NV, Pallor, Diaphoresis -> Inc LFT & AST -> Encephalopathy, coma, death. (inc LFT abn PT/INR)
    Tylenol

    • Charcoal
    • Mucomist 
    • Acetadote
  8. Mydriasis, Anorexia, Anxious, Agitation, Tachy, HTN, MI, Seizures, Hyper-Gly, Hyper-Therm, Rabo
    Amphetamines & Stimulent

    • SX: Benzo/ Barbs, Propofol, Haloperidol, Nitro, CaCB
  9. Red, Hot, Dry, Blind, Mad x2
    Anticholinergic

    • Benzo or Antipsyc for agitation
    • Physostigmine for annit cholinergic effects
    •      !!(not for cyclic antidepressants)!!
    • -mainly for drugs with anti- m properties; Atropine, scopolamine, benztropine, trihexyphenidyl 

  10. Hyperthermia
    HTN
    HoTN
    CNS excitation
    SS MOI OD

    • SX:
    • Cool bath
    • Phentolamine
    • Epi.Nepi
    • Benzo
  11. ST
    Torsades
    HoTN
    Seizure
    Cyclic OD

    • NA Bicarb
    • Mg sulfate
    • Fluid bolus
    • Benzo, Barb
  12. Hyperthermia - Auto dysfxn - AMS - Muscular Rigidity
    Antipsycotic 

    • Benzo
    • Thiamine + Dextrose
    • Na Cl bolus (vasopressors) Epi, NEpi
    • Na Bicarb IV drip and a 2nd line with Lidocaine IV
  13. Altered glucose metabolism, Hypoxia, Tachy, seizures, NV, coma, agitation, Hypo K, dec motility, pyloric spasm, Proteinurea, tubular damage.
    Salicylates (Aspirin)

    • AC
    • WBI
    • Na Bicarb to alkalize the urine (1st line)
    • Hemodyalysis (2nd line)
  14. Seizure, coma, delirium, Rsp. depression, Brady, HoTN, Hypoglycemia
    Beta blocker

    • glucagon
    • Ca Gluconate (lol)
  15. Sedation, Resp. depression
    Benzo

    Flumazenil (Romazicon)
  16. Acute pulm injury, Brady, HoTN, Hyper-glycemia
    CCB (Dehydor-pines)

    • AC
    • WBI
    • Atropine
    • Ca
    • NE
    • Glucagon
    • Insulin and Glucose
  17. Shock, CV collapse, HoTN, Disrhythmia
    Digoxen

    • DSfab or Digifab
    • se: decreases free serum dig by inc excretion and dec serum K

  18. Miosis, Seizure, Resp depression, Brady, HoTN
    Opioids

    Narcan

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