Respiratory Viruses

The flashcards below were created by user flucas on FreezingBlue Flashcards.

  1. Which of the follwing is FALSE about respiratory viruses?

    A. usually, increased mortality with influenza and respiratory syncytial virus infection in the infirmed and elderly
    B. generally have a short incubation period
    C. they are characterized by a seasonal occurrence and community epidemiology
    D. herpesvirus can be classified as a respiratory virus
    E. respiratory syncytial virus (RSV) is typically treated with neuraminidase inhibitors and M2-ion-channel blockers
    E. respiratory syncytial virus (RSV) is typically treated with neuraminidase inhibitors and M2-ion-channel blockers
    (this multiple choice question has been scrambled)
  2. What are some common features of respiratory virus infection?
    • baceterial superinfection
    • person-to-person transmission
    • multiple infections with each virus
    • overlapping spectrum of diseases
    • short inucabation period (days)
    • world-wide distribution
    • seasonal
  3. What are the common viral causes of the common cold? What are the less common causes?
    • common: rhinovirus, coronavirus
    • less common: influenza, parainfluenza, enterovirus, adenovirus
  4. What are the common diagnostic tools used to detect respiratory viruses?
    • culture
    • antigen detection
    • nucleic acid detection (PCR)
    • serology
  5. What are the fundamental differences between antigenic shift and antigenic drift?
  6. What are the common viruses associated with "the flu"? What are the less common viral associations?
    • common: Influenza A or B
    • less common: parainfluenza, adenovirus
  7. Parainfluenza 1-3, respiratory syncytial virus (RSV), measles virus, and human metapneumovirus are all part of which group of viruses? What is their genetic structure?
    • paramyxoviruses
    • (-)sense ssRNA
  8. True or False: Changing 2 positions in the HA (hemagglutin) receptor-binding domain (i.e. changing the receptor usage in the upper and lower respiratory tract) can enable avian influenza strains become transmissibe as a respiratory virus from person-to-person.
  9. What are some neuraminidase inhibitors and whare are they used to treat?
    • e.g. zanamavir
    • e.g. oseltamavir

    used to treat influenza
  10. What are some M2-ion-channel blockers and what are they used to treat?
    • e.g. amantadine
    • e.g. rimantadine (limited use because of resistance)

    used to treat influenza
  11. What are the common treatments for respiratory syncytial virus (RSV)?
    • ribavirin
    • RSV-IGIV
    • monoclonal antibody (e.g. palivizumab)
  12. What are the single-stranded, (-) sense RNA respiratory viruses?
    • othomyxovirus (e.g. influenza A & B)
    • paramyxoviruses (e.g. parainfluenza 1-3, RSV, measles virus, human metapneumovirus)
    • Bunyavirus (e.g Hantavirus)
  13. What is Croup?
  14. What traits do ortho- and para-myxoviruses have in common?
    • respiratory pathogens
    • (-)sense, ssRNA
    • helical nucleocapsid
    • enveloped
    • bud from cell surface
  15. How do ortho- and para-myxoviruses differ?
    • genome segmentation
    • site of entry
    • primer requirement
    • site of RNA synthesis
    • rate of recombination
  16. Which respiratory viruses have animal repositories?
    • influenza A
    • coronavirus
  17. What are the common and uncommon respiratory viruses?
    • common:
    • (2)adenovirus
    • coronavirus
    • (3)rhinovirus/enterovirus
    • (1)RSV
    • parainfluenza virus
    • human metapneumovirus
    • influenza viruses
    • (4)human bocavirus (parvovirus) --> only an association with human disease

    • less common:
    • herpesviruses
    • hantavirus
    • reoviruses
    • enteroviruses
  18. What are the common and less common viral causes of Croup?
    • common: parainfluenza
    • less common: influenza, RS, adenovirus
  19. What are the common and less common viral causes of bronchiolitis?
    • common: RSV, human metapnumovirus
    • less common: influenza, parainfluenza, adenovirus
  20. What are the common and less common viral causes of pneumonia?
    • common: influenza, adenovirus, RSV
    • less common: parainfluenza, measles, VZV, CMV
Card Set:
Respiratory Viruses
2010-05-13 04:55:45
respiratory viruses microbiology

Respiratory Viruses: Influenza, Respiratory Syncytial Virus (RSV)
Show Answers: