► partly depends on probability of collision between drug and receptor
►At low [D], collision likely/unlikely, binding unlikely; i.e. low [DR]
►As [D] increases, collisions increase, likelihood of binding increase/decreases; i.e. [DR] increases
►Relationship is on a linear concentration scale (x-axis)
►… but sigmoidal on a logarithmic scale
- ►Binding partly depends on probability of collision between drug and receptor
- ►At low [D], collision unlikely, binding unlikely; i.e. low [DR]
- ►As [D] increases, collisions increase, likelihood of binding increases; i.e. [DR] increases
- ►Relationship is parabolic on a linear concentration scale (x-axis
- )►… but sigmoidal on a logarithmic scale