Q2 Clopidogrel (Plavix)

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Author:
tville01
ID:
193137
Filename:
Q2 Clopidogrel (Plavix)
Updated:
2013-01-17 09:20:16
Tags:
Q2 Clopidogrel Plavix
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Description:
Q2 Clopidogrel (Plavix)
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  1. Route of clopidogrel (Plavix)
    • PO-75 mg qd
    • 300mg 1* after coronary stent
  2. MOA of clopidogrel (Plavix)
    Alters platelet aggreagation by altering platelet membrane so it can’t receive signals to aggregate and form a clot
  3. Class of clopidogrel (Plavix)
    • Antiplatelet
    • ADP inhibitor
  4. Indications for clopidogrel (Plavix)
    • ↓ Thrombolytic MI
    • Prophylaxis TIA
    • Post MI thrombosis prevention
  5. Contraindications for clopidogrel (Plavix)
    • Allergy
    • Thrombocytopenia
    • Bleeding
    • Leukemia
    • GI ulcer
    • Vitmain K deficiency
    • Recent stroke
  6. Adverse effects of clopidogrel (Plavix)
    • Cardio- chest pain, HTN, edema,
    • CNS- flu-like, HA, dizzy fatigue,
    • GI- abd pain, dyspepsia, diarrhea, nausesa
    • Other-nose bleed, rash, puritis(itching)
  7. Interactions with clopidogrel (Plavix)
    Dipyridamole-additive platelet activity → increased bleeding potential
  8. clopidpgrel is better than aspirin at
    prevention of MI, CVA, and vascular deaths

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