Q2 Heparin

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Author:
tville01
ID:
193387
Filename:
Q2 Heparin
Updated:
2013-01-17 09:32:18
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Q2 Heparin
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Description:
Q2 Heparin
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  1. Routes for Heparin
    • IV-20,000-40,000 unit QD
    • Subcu-5,000 units Q8-12 h(prophylaxis)
  2. MOA of heparin
    Binds to antithrombin III, which turns off three main activating factors which turns off coagulation pathway

    factorII(thrombin) most sensitive to heparin
  3. Class of heparin
    Anticoagulant
  4. Indications for heparin
    • Thrmbosis/emolism
    • DVT/PE prophylaxis
    • clotting prevention
  5. Contraindications of heparin
    • Allergy
    • Acute bleeding
    • thrombocytopenia
  6. Adverse effects of heparin
    • Bleeding
    • Hematoma
    • Nausea
    • Anemia
    • Fever
    • Edema
    • HIT(heparin induced thrombocytopenia)
  7. Interactions with heparin
    • Lovenax
    • NSAIDS
    • Anticoagulants
    • Thrombolytics
    • Ceohlasporines
    • Penicillin
  8. When heparin is given IV what should be monitored
    aPTT
  9. What should you so if HIT II occurs
    discontinue- may lead to paradoxical thrombosis
  10. What are S&S of heparin overdose
    • hematuria
    • melena(stool blood)
    • petechia
    • ecchymosis
    • bleeding gums
  11. What can reverse the effects of heparin if overdose occurs
    • protamine
    • packed RBC

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