Quarter 2 Spinal neurology Sec 2 inflammation

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Author:
bradley.knox
ID:
193491
Filename:
Quarter 2 Spinal neurology Sec 2 inflammation
Updated:
2013-01-18 20:56:34
Tags:
spinal neurology
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Description:
sp neu
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  1. What are the five cardinal signs of inflammation?
    • Redness
    • Hotness
    • Swelling
    • Pain
    • Loss of function
  2. What cardinal sign is caused by fluid release, chemicals, biproducts, and microirritations
    Pain
  3. What are the three events of acute inflamation?
    • 1. Vasodilation
    • 2. Vascular leakage and edema
    • 3. Leukocyte emigration (phagocytosis)
  4. What occurs briefly before vasodilation?
    vasoconstriction
  5. What acute inflammation event causes warmth / redness, opens microvascular bed, and increases the intravascular pressure
    Vasodilation
  6. Where does fluid build up during edema?
    between cell and tissue
  7. what type of vascular leakage does inflammation cause?
    Exudate release 
  8. What would be seen in fluid the is released due to exudate release?
    • High Density fluid
    • immunoglobins
    • leukocytes
  9. What do histamines, bradykinins, and leukotrienes cause and in what stage of inflammation?
    • Immediate transient endothelial cell contraction 
    • During first 15 to 30 min of vascular leakage (in vanules only)
  10. What is it called when when leukocytes move toward gap in endothelium?
    margination and rolling
  11. What mediates early rolling adhesion?
    • E-Selectin (endothelium)
    • P-Selectin (platelets)
    • L-Selectin (leukocytes)
  12. What are the first white blood cells to transmigrate (Diapedesis)
    Polymorphic Neutrophils (PMN) (phagocytes)
  13. What cells recognize what needs to be attacked?
    T-Lymphocytes
  14. What cells build the immunolgobin. 
    B-Lymphocytes
  15. What are cytokines, LTB4, Soluble bacterial products, complement component C5
    Chemotaxis 
  16. What chemotaxis are used to communicate between cells?
    Cytokines

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