MED-Adenosine

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Author:
amerelman
ID:
19361
Filename:
MED-Adenosine
Updated:
2010-05-15 15:19:48
Tags:
MED Adenosine
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Description:
MED-Adenosine
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  1. Functional Class
    Antidysrhythmic
  2. Mechanism of Action
    • Naturally occurring nucleoside
    • Decreases conduction through the AV node
    • Interrupts AV and SA re-entry pathways restoring NSR in patients with SVT
  3. Indications
    SVT refractory to vagal maneuvers including WPW
  4. Contraindications
    • Hypersensitivity
    • 2nd and 3rd Degree blocks
    • Symptomatic bradycardia
    • Sick sinus syndrome
  5. Precautions
    • Use semi-fowler's position as patients will usually develop dysrhythmias at time of conversion
    • Asthma
  6. Side Effects
    • Syncope
    • Dizziness
    • Dyspnea
    • N/V
    • Headaches
    • Palpitations
    • CP
    • Hypotension
    • Dysrhythmias
  7. Interactions
    • Caffiene and Xanthines (aminophylline or theophylline) may require higher dose
    • Dipyridamole and Carbamazepine may need smaller doses
  8. Dose/Route
    • ADULT
    • 6 mg rapid IVP followed by 10-20 mL NS flush
    • If no conversion in 1-2 minutes administer
    • 12 mg rapid IVP followed by 10-20 mL NS flush
    • If no conversion in 1-2 minutes administer
    • 12 mg rapid IVP followed by 10-20 mL NS flush

    • PEDI
    • 0.1 mg/kg IVP/IO (max single dose 6 mg)
    • May repeat once in 1-2 mins
    • 0.2 mg/kg IVP/IO (max second dose 12 mg)
  9. Pharmacokinetics
    • Onset=Rapid
    • Half-Life= approximately 10 seconds

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