exaplain the 8 steps in the heartworm life cycle
1- Adults mating in the pulmonary arterie in the heart. Produce microfilaria (L1)
2-microfilaria circulate in the blood stream. Mosquito takes a blood meal and ingests 1-3 L1s.
3-L1 moults into L3 inside the mosquito.
4-Mosquito takes another blood meal and L3 enter the bite wound through the saliva into the host.
5- L3-L4 in 3-4 days
6- L4 migrates through muscle layers which takes 50-70 days until it reaches the neck.
7- L4 moults into L5 and penetrates a blood vessel in the neck migrating to the pulmonary artery.
8- L5 takes 4.5 months to moult into an adult and reproduce in the pulmonary artery the whole cycle from L1 ingestion to adult takes 6.5 months.