LAT SET 1.csv

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  1. 1. What is in vitro research?
    "1. Research done outside a living animal
  2. 2. What is in vivo research?
    2. Research using living animals
  3. 3. What is the difference between applied research and basic research?
    "3. In applied research
  4. 4. What is the difference between a control group and an experimental group?
    4. The experimental group is the one that is subjected to all of the manipulations that are being studied. A control group is not subjected to all the manipulations and is used as a comparison for the results of the experimental group.
  5. "5. Prior to conducting an experiment
    an investigator defines the hypothesis. What is the hypothesis?"
  6. 6. What are examples of ways that an animal technician can introduce unintended variables into a study?10. What is the name of the document that a P.I. must complete and have approved before he/she can start a project that uses animals?
    "6. By not giving an animal the proper food
  7. 7. What does P.I. stand for?
    7. Principal Investigator
  8. 8. What are some examples of the types of information that an investigator must provide in an animal research protocol to be submitted to the IACUC? And what does IACUC stand for anyway?
    "8. The names and qualifications of the people involved in the study
  9. 9. How often is the IACUC required to review an institution�s animal care and use program and inspect the animal facilities?
    9. Once every six months
  10. 10. What is the name of the document that a P.I. must complete and have approved before he/she can start a project that uses animals?
    10. Animal Protocol
  11. 11. Who has to comply with the Public Health Service (PHS) Policy on Humane Care and Use of Laboratory Animals?
    11. Any facility that receives grant money from the federal government to perform studies that involve live vertebrate animals
  12. 12. What are the three primary responsibilities of the IACUC as outlined in the PHS Policy on Humane Care and Use of Laboratory Animals? Who does the policy require be on the committee? Who appoints the IACUC?7. What does P.I. stand for?
    "12. (1) Review an animal facilities program for animal care and use and inspect the animal facilities
  13. 13. Research institutions that are required to comply with the PHS Policy must provide the Office of Laboratory Animal Welfare (OLAW) with a signed agreement that outlines how the institution complies with all aspects of the Policy. What is that agreement called
    13. The Letter of Assurance
  14. 14. Who has to comply with the Institute of Laboratory Animal Resources (ILAR) Guide for the Care and Use of Laboratory Animals?
    14. Any facility that receives grant money from the federal government to perform studies that involve live vertebrate animals
  15. 15. Who has to comply with the United States Department of Agriculture (USDA) Animal Welfare Act regulations and when were those regulations originally enacted? Specifically which animals do these regulations apply to? Does it cover wild rats and mice?
    "15. Facilities who use any mammal in research with the exception of laboratory rats
  16. 16. Which organization is responsible for ensuring compliance with the Animal Welfare Act?
    16. United States Department of Agriculture (USDA)
  17. 17. How often does USDA inspect research facilities?
    17. Once a year
  18. 18. Which regulatory organization registers institutions using experimental animals?
    18. USDA
  19. 19. Who has to comply with the Food and Drug Administration (FDA) Good Laboratory Practices regulations? For how long do records related to a GLP study need to be maintained?
    "19. . Facilities who use animals to perform safety studies of food additives
  20. 20. What regulatory agencies regulate how big cages used to house research animals must be?
    "20. ILAR and USDA
  21. "
  22. "21. What does AAALAC stand for and what do they do? Is accreditation mandatory or voluntary? What is the primary document AAALAC uses when evaluating an animal facility? Once accredited
    how often does AAALAC reevaluate an institution?"
  23. 22. What does F.O.I.A. stand for?
    22. Freedom of Information Act
  24. 23. Which organization regularly publishes a report evaluating the various methods of euthanizing animals?
    23. American Veterinary Medical Association (AVMA)
  25. "24. Is it true that the USDA
    as described in the Animal Welfare Act
  26. 25. How long after completion of a project does OLAW require that the IACUC retain records such as the animal use protocol?
    25. Three years
  27. 26. Which agency has guidelines for the use of biohazardous pathogens?
    26. Center for Disease Control (CDC)
  28. 27. What regulatory agency has the most regulations specific to transportation?
    27. USDA
  29. 28. What organization wrote the Guide for the Care and Use of Laboratory Animals?
    28. Institute for Laboratory Animal Resources (ILAR)
  30. 29. What organization has a program for certifying laboratory animal technicians?
    29. American Association for Laboratory Animal Science (AALAS)
  31. 30. Which committee requires a member of the community be on it so that community input can be obtained?
    30. Institutional Animal Care and Use Committee (IACUC)
  32. 31. How often should every research animal be checked?
    "31. At least once everyday
  33. 32. Who is the most important person in making sure animals in a research facility are OK?
    32. The animal care technicians
  34. 33. What does AALAS stand for and who are they?
    "33. American Association for Laboratory Animal Science; they are an association of people and institutions concerned with the production
  35. 34. Why can�t the use of cell or tissue culture replace the use of animals in research?
    "34. Two reasons. First
  36. 35. Why can�t the use of mathematical or computer models replace the use of animals in research?
    35. Because we don't know all there is to know about any animal and therefore can't create a mathematical or computer model that could tell us all that using a living animal can
  37. 36. What are the three �R�s�?
    "36. Reduction
  38. 37. List as many reasons as you can think of why it is good to have Standard Operating Procedures (SOP�s).
    37. So that all procedures are done in a uniform and consistent way which will minimize the stress of the animals and ensure that quality care be provided
  39. 38. What does IACUC stand for and who must be on it?
    "38. Institutional Animal Care and Use Committee; a veterinarian
  40. 39. Why is it important to maintain records of all that occurs in an animal facility?
    "39. So that you have clear documentation of all activities that have occurred at the facility; these records then provide evidence for regulatory agencies
  41. 40. What information should be contained on a cage card?
    "40. The species
  42. "41. With the exception of official USDA dog and cat tags
    how long do the various types of required records need to be maintained?"
  43. 42. How long do official USDA dog and cat tags need to be maintained?
    42. Two years after the dog has been either adopted out or euthanized
  44. "43. When USDA does an inspection of an animal facility
    how much notice must provide before arriving?"
  45. "44. According to PHS
    how long do records such as animal protocols need to be maintained after a project is completed?"
  46. 45. What does �per diem� mean?
    45. The amount of money it costs to maintain each animal each day (the cost per animal per day)
  47. 46. What is a cost center?
    "46. A category of costs associated with maintaining animals (i.e. labor
  48. "47. What does DEA stand for and what
    in the laboratory animal setting
  49. 48. Who wrote the three R�s?
    48. Russell and Birch wrote the three R�s
  50. 49. How far in advance of a site visit is USDA required to provide notification of the visit to a facility?
    49. USDA is not required to provide any advance notification.
  51. 50. Which of the three R�s is being addressed by using fewer animals in an experiment?
    50. Reduction
  52. 51. Which of the three R�s is being addressed by working out the kinks of a surgical procedure by practicing on cadavers first?
    51. Refinement
  53. 52. Which of the three R�s is being addressed by using in vitro technique in place of animals?
    52. Replacement
  54. "53. There are two organizations with the acronym NRC
    the Nuclear Regulatory Commission and the National Research Council. Which one is ILAR a part of? What is the role of the other one?"
  55. "54. If a disease occurs spontaneously in an animal
    would that animal be considered a natural or an induced animal model for the study of that disease?"
  56. 55. What does FOIA stand for? To whom does the FOIA apply?
    55. FOIA stands for the Freedom of Information Act. That act enables any member of the public to request copies of any records from any public institution. It doesn't apply to private companies.
  57. 56. What does NRC stand for and what does that organization do?
    56. NRC stands for the Nuclear Regulatory Commission and they regulate the use of radioisotopes and radiation.
  58. 57. What does CMAR stand for and what is it?
    57. CMAR stands for Certified Manager of Animal Resources. It is a certification offered to animal resource managers by AALAS.
  59. 58. What are two organizations that require that you be a veterinarian to be a member?
    58. ACLAM and ASLAP
  60. 59. What does GLP stand for?
    59. Good Laboratory Practices
  61. "60. With respect to the three ""R's""
    which of them would be addressed when an investigator uses a new surgical technique that causes less trauma to an animal and will therefore require a shorter recovery time for the animal?"
  62. "61. With respect to the three ""R's""
    which of them would be addressed when after a surgical procedure is performed
  63. 62. How many members does the PHS Policy require be on an animal care and use committee?
    62. Five
  64. 63. What is meant by the phrase �established performance standards�?
    63. thorough descriptions of how tasks should be performed
  65. 64. What should an employee�s performance evaluation be based on?
    64. the employee�s position description and established performance standards
  66. 65. Which of the following is an element of how a supervisor should assign a duty to an employee?
    "65. a thorough explanation of how the task is to be performed
  67. "66. If you are assigned a difficult task
    • how should you approach it?"
    • 66. do it at your best time
  68. "67. If you are an IACUC coordinator responsible for keeping records and buried in a filing cabinet you find an animal protocol that expired 18 months ago
    can you throw it away?"

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