pharma

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Author:
harryharrie
ID:
194326
Filename:
pharma
Updated:
2013-01-21 20:30:24
Tags:
cardiac
Folders:

Description:
arryhtmia
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  1. quinidine(1a na block)
    • 1.antiarrythmic.antimuscarinic,alpha blocker.
    • 2.initial digitalisation required for AF
    • 3.adv:cinchonism:tinnitus headache ocular G.I.dysfunction torsades.
    • 4.displace digoxin frm tissuebindin sites
    • ¬† ¬†hyperkalemia enchances effect
  2. procainamide(1a na block)
    antiarrythmic,hapten,metabolised by acetylization,binds to tissueproteins(SLE like syndrome),hematoxicity,torsades.
  3. SLElike syndrome
    • hydralazine
    • isoniazid
    • procanamide
    • antihistones more specific
  4. lidocaine(1b na block)
    • post MI
    • digoxin toxicity
    • openheartsurgery
    • advrse;;;seizures,least cardiotoxic
    • always used i.v...so oral drugs in dis class are mexiletine,tocainide.
  5. flecainide,propafenone(1c na block)
    • last resort in refractory cases
    • potent proarrythmic so not much used.

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