AP II- blood comp therapy part 2

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Anonymous
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194569
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AP II- blood comp therapy part 2
Updated:
2013-01-22 21:47:13
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AA Emory anesthesia blood therapy
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AP II monroe lecture part 2
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  1. 4 reasons to transfuse blood
    • 1- extensive blood loss
    • 2- inadequate perfusion
    • 3- low Hgb
    • 4- poor coagulation
  2. For a 70 kg pt, after what amount blood loss should you send labs?
    1-1.5 L
  3. Define PRBC
    Packed Red Blood Cells
  4. PRBC is indicated for treatment of _______
    anemia
  5. What is the volume of 1 unit PRBC? (ml)
    250-300 mL
  6. What is the Hct % in 1 unit of PRBC's?
    70-80%
  7. What percentage of blood volume lost would indicatate  definite rapid PRBC transfusion?
    >40%
  8. what Hgb level indicates PRBC transfusion?
    less than 7 g/dL
  9. How much will one unit of PRBC's increase hemoglobin and Hct?
    • Hgb- 1g/dL
    • Hct- 3%
  10. Do you warm PRBC's before administration?
    YES!
  11. What fluid should not be used when admin PRBC's?
    LR- Calcium can cause clotting
  12. What size filter should be used when admin PRBC's?
    150 microns
  13. name the 3 types of PRBCS
    • washed
    • leukocyte reduced
    • irradiated
  14. What is "WASHED PRBCS"? what is removed from this fluid?
    • centrifuged in saline
    • removes K+ excess
  15. Who should receive "WASHED PRBCS"?
    pt w/ hx of transfusion rxn
  16. how long can "WASHED PRBCS" be stored?
    24 hours
  17. what is the most effective method of creating "Leukoctye-reduced" PRBC's?
    filtered
  18. "Leukoctye-reduced" PRBC's are given to avoid __________ febrile reactions.
    nonhemolytic
  19. "Leukoctye-reduced" type PRBC's are given to prevent sensitization of patients with ______ _______.
    aplastic anemia
  20. "Leukoctye-reduced" PRBC's are given to  minimize transmission of what two viruses?
    HIV and CMV
  21. Cell saver produces what percent Hct from salvaged surgical field blood?
    65-70%
  22. should Cell saver blood be warmed?
    No- it doesnt need to be
  23. Cell saver blood should be filtered through a ___ micron filter
    40
  24. Should Cell saver be pressurized>?
    NO!
  25. what should never be clamped when using a cell-saver?
    the delivery line
  26. what is normal platelet level?
    100-400k
  27. platelet transfusion is indicated when plt count is < __________.
    50,000 cells/mm^3
  28. platelets are routinely given after what procedure and why?
    • cardiopulmonary bypass
    • restore normal coagulation
  29. what 2 ways are platelets prepared?
    multiple or single donor
  30. initial does of platelet transfusion?
    10cc/kg
  31. how much will a "6 pack" whole blood platelet unit raise a platelet count?
    30-50 x 10^9 /L
  32. Should platelets be warmed or cooled?
    NO to both
  33. what size filter should be used for platelet transfusion?
    150 micron
  34. why should 20-40 micron filter not be used for platelet transfusion?
    it will remove most of the platelets
  35. What is Fresh Frozen plasma?
    fluid portion obtained from a single unit of whole blood, frozen within 6 hours of collection.  PLATELETS + PLASMA
  36. FFP is indicated when PT, PTT or both are ___ times greater than normal
    1.5
  37. FFP can be used to reverse _______ therapy.  ___ - ____ ml/kg is sufficient to cause this effect.
    • warfarin
    • 5-8
  38. 10-15 ml/kg FFP will raise coagulation proteins what percentage?
    25-30%

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