AP II- blood comp therapy part 2

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AP II- blood comp therapy part 2
2013-01-22 21:47:13
AA Emory anesthesia blood therapy

AP II monroe lecture part 2
Show Answers:

  1. 4 reasons to transfuse blood
    • 1- extensive blood loss
    • 2- inadequate perfusion
    • 3- low Hgb
    • 4- poor coagulation
  2. For a 70 kg pt, after what amount blood loss should you send labs?
    1-1.5 L
  3. Define PRBC
    Packed Red Blood Cells
  4. PRBC is indicated for treatment of _______
  5. What is the volume of 1 unit PRBC? (ml)
    250-300 mL
  6. What is the Hct % in 1 unit of PRBC's?
  7. What percentage of blood volume lost would indicatate  definite rapid PRBC transfusion?
  8. what Hgb level indicates PRBC transfusion?
    less than 7 g/dL
  9. How much will one unit of PRBC's increase hemoglobin and Hct?
    • Hgb- 1g/dL
    • Hct- 3%
  10. Do you warm PRBC's before administration?
  11. What fluid should not be used when admin PRBC's?
    LR- Calcium can cause clotting
  12. What size filter should be used when admin PRBC's?
    150 microns
  13. name the 3 types of PRBCS
    • washed
    • leukocyte reduced
    • irradiated
  14. What is "WASHED PRBCS"? what is removed from this fluid?
    • centrifuged in saline
    • removes K+ excess
  15. Who should receive "WASHED PRBCS"?
    pt w/ hx of transfusion rxn
  16. how long can "WASHED PRBCS" be stored?
    24 hours
  17. what is the most effective method of creating "Leukoctye-reduced" PRBC's?
  18. "Leukoctye-reduced" PRBC's are given to avoid __________ febrile reactions.
  19. "Leukoctye-reduced" type PRBC's are given to prevent sensitization of patients with ______ _______.
    aplastic anemia
  20. "Leukoctye-reduced" PRBC's are given to  minimize transmission of what two viruses?
    HIV and CMV
  21. Cell saver produces what percent Hct from salvaged surgical field blood?
  22. should Cell saver blood be warmed?
    No- it doesnt need to be
  23. Cell saver blood should be filtered through a ___ micron filter
  24. Should Cell saver be pressurized>?
  25. what should never be clamped when using a cell-saver?
    the delivery line
  26. what is normal platelet level?
  27. platelet transfusion is indicated when plt count is < __________.
    50,000 cells/mm^3
  28. platelets are routinely given after what procedure and why?
    • cardiopulmonary bypass
    • restore normal coagulation
  29. what 2 ways are platelets prepared?
    multiple or single donor
  30. initial does of platelet transfusion?
  31. how much will a "6 pack" whole blood platelet unit raise a platelet count?
    30-50 x 10^9 /L
  32. Should platelets be warmed or cooled?
    NO to both
  33. what size filter should be used for platelet transfusion?
    150 micron
  34. why should 20-40 micron filter not be used for platelet transfusion?
    it will remove most of the platelets
  35. What is Fresh Frozen plasma?
    fluid portion obtained from a single unit of whole blood, frozen within 6 hours of collection.  PLATELETS + PLASMA
  36. FFP is indicated when PT, PTT or both are ___ times greater than normal
  37. FFP can be used to reverse _______ therapy.  ___ - ____ ml/kg is sufficient to cause this effect.
    • warfarin
    • 5-8
  38. 10-15 ml/kg FFP will raise coagulation proteins what percentage?