Card Set Information
Animal Diseases Two
What is neoplasia?
uncontrolled growth of cells whose proliferation cannot be adequately controlled by normal regulatory mechanisms in normal tissues
Why is cancer called "cancer"?
latin word for crab
tumors invade tissues like crawling crabs
What does the word tumor mean?
What are some other names for tumor?
What is oncology?
the study of neoplasia
What is the proliferation of normal cells regulated by?
genetic program of each cell
signals transmitted between cells by direct contact
various soluble substances which have growth promoting or inhibiting effects
What happens once cells stop proliferating?
they assume specialized functions by activating specific genes and suppressing unneeded genes
Do cancer cells usually achieve the same level of differentiation as normal cells?
Describe the growth of a tumor cell.
How is the growth of a tumor cell autonomous?
independent of growth factors and stimuli that promote the growth of normal cells
How is the growth of a tumor cell excessive?
do not respond to normal regulations of cell proliferation - growth does not stop
How is the growth of a tumor cell disorganized?
random growth - does not try to form normal tissue
Can more than one type of neoplasia occur in an individual?
Are all cells in a tumor neoplastic?
supportive elements are not neoplastic - connective tissue, blood vessels
What can interfere with the recognition of a tumor?
Can spontaneous regression of neoplasia occur?
Can tumors develop from any cell type?
What are the different types of neoplasia of the spleen?
hemangiosarcoma (blood vessels)
What are the different types of neoplasia of the skin?
sebaceous adenomas (oil glands)
lipomas (adipose cells)
Not all masses are neoplasms. What types of masses are not neoplastic?
hyperplastic nodules (spleen, prostate, mammary)
Not all neoplasms are masses. What are some neoplasms that are not masses?
leukemia (malignant cells in circulation)
diffuse infiltration or enlargement of an organ
Does the size of the tumor indicate the degree of malignancy?
tiny tumors can be malignant, large tumors can be benign
Can neoplasia be present as a non-healing lesion or as an ulcerated mass?
Is neoplasia usually a different color from adjacent normal tissue?
Can we identify neoplasia by a gross exam?
microscopic identification is needed
Why is important to identify the specific type of neoplasia?
for prognosis, treatment, and to predict the behavior of the tumor
What is the role of the LVT regarding neoplasia?
recognize potential neoplasms (grossly and microscopically)
may observe tumor cells in sediment cytology of urine, body cavity fluid, blood smears, aspirates
prepare tissue for cytology