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  1. Penicillins(Ampicillin, Pen G, Pen V, Amoxicillin, Augmentin)
    SE: Skin rashes, diarrhea, allergic reactions, renal, hepatic, hematological, abnormalities, N/V
    C/S, Hx of Penicllin reaction, Observe for 20 minutes post IM injection,Monitor for loose, foul-smelling stool and change in tongue, give 1 hour before and 2 hr after food
  2. Sulfsoxazole
    SE: HA, GI disturbances, allergic rash, urinary crystallization
    IO, force fluids, maintain alkalin urine, bicarb, avoid vitamin c - acidifies urine
  3. Sulfasalazine
    SE: N/V Skin eruption, agranulocytosis
    • Advise client to avoid exposure to sunlight,
    • 3,000ml to avoid crystal formation
  4. Trimethoprin/Sulfamethoxazole
    SE: Hypersensitivity reaction, blood dyscrasias, rash
    CS before first dose, IV solution must be given slowly over 60-90 minutes, Never admin IM, 3,000ml fluids per day
  5. Tetracycllines(Tetracycline, Panmycin)
    SE: Photosensitivity, GI upset, renal, hepatic, hematological abnormalities, dental discoloration of decidous teeth, enamel hypoplasia
    Give between meals, IF GI symptoms occur, administer with food except milk product or other  food high in calcium(interferes with absorption) assess for change in bowel habits, black tongue, no for kids, IO, no sun b/c sunlight turns into toxic
  6. Aminoglycosides(Gentamicin, tobramycin, amikacin)
    SE: ototoxicity cranial nerve VIII, Nephrotoxicity
    Check cr and BUN, check peak-2 h after med given, check trough- at time of dose/prior to med, Monitor for symptoms of bacterial overgrowth, photosensitivity, teach to immediately report tinnitus, vertigo, nystamus, ataxia and IO, audiograms if given long term
  7. Fluoroquinolones Ciprofloxacin(Cipro)
    SE: Seizures GI upset Rash
    • Contraindicated in children less than 18 year of age
    • Give 2 hours pc or 2 hours before an antacid or iron prep, avoid caffeine
  8. Macrolides
    Azithromycin, Erythromycin
    SE: pain at injection site, N/D
    Can be used in clients with compromised renal function because excretion is primarily through the bile
  9. Cephalosporins(Cector, Ancef, suprax, Keflex, Rocephin, Cefoxitin)
    SE: N/D, dizziness, abdominal pain, eosinophilia, superinfections
    can cause false positive coombs test, cross sensitivity with pencillins, take careful history of pencillin reaction
  10. glycopeptides
    SE: Liver damage
    Poor absorption orally, but IV peak 5 minutes duration 12-24 hrs, avoid extravasation, give antihystamine if red man syndrome, dec bp or flushing of face and neck
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2013-01-28 03:05:35

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