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Serum Albumin
- Normal: 3.5- 5.0 g/dl, visceral protein
- a. Maintains colloidal osmotic pressure
- b. Hypoalbuminemia assoc w/ edema
- c. Levels above normal likely due to dehydration
- d. Long half-life does not reflect current protein intake
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Serum Transferrin
- Normal > 200 mg/dl visceral protein
- a. Serum level controlled by iron storage pool
- b. Rises with Ff def
- c. Can be determined from TIBC
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TTHY
- Transthyretin, PAB prealbumin
- Normal 16-40 mg/dl
- a. Short half-life
- b. Picks up changes in protein quickly
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Retinol-Binding Protein RBP
- Normal 3-6 mg/dL
- a. circulates w/ prealbumin
- b. Shortest half-life (12 hours)
- c. Binds and transports retinol
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Hct Hematocrit
- Normal Men: 44%, Women: 38%, Preg: 33%
- a. volume of packed cells in whole blood
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Hgb Hemoglobin
- Normal Men: 14-17mg/dL, Women: 12-15 gm/dL, Preg: <= 11 mg/dL
- a. Fe- containing pigment of RBCs
- b. Erythrocytes are produced in bone marrow
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Serum Ferriting
- Normal Male: 12-300 ng/mL, Female: 10-150 ng/mL
- a. Indicates size of Fe- storage pool
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Serum Creatinine
- Normal 0.6-1.4 mg/dL
- a. Related to muscle mass; measures somatic protein
- b. May indicate renal disease, muscle wasting
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CHI
- Creatinine Height Index
- Normal 80%
- a. Ratio of creatinine excreted/ 24 hours to height
- b. Estimates lean body mass- somatic protein
- c. 60-80% is mild muscle depletion
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BUN
- Normal 10-20 mg/dL
- a. Related to prtein intake
- b. Indicator of renal disease
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BUN: Creatinine
Normal 10-15: 1
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Urinary Creatinine Clearance
- Normal 115 +/- 20 ml/ min
- a. measures GFR
- renal function
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TLC
- Total lymphocyte count
- Normal > 2700 cells/cu mm
- a, Measures immunocompetency
- b. Moderate depletion 900-1800
- c. Severe depletion <900
- d. Decreased in protein-energy malnutrition
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CRP
- C-Reactive protein
- a. marker of acute inflammatory stress
- b. As it declines, indicates when nutrition therapy would be beneficial
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FEP
- Free erythrocyte protoporphyrin
- a. Direct measure of toxic effects of lead on heme synthesis
- b. Increased in lead poisoning
- c. Lead depletes iron leading to anemia and displaces Ca in bone --> Zn def
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PT
- Prothrombin time
- Normal 11-12.5 seconds; 85-100%
- a, anticoagulants prolong PT
- b. Evaluates clotting adequacy
- c. Change in Vit K intake will alter rate
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Hair Analysis
Not for nutritional assessment. Useful in measuring intake of toxic metals.
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