Biochemical analysis

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Author:
lincook
ID:
196327
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Biochemical analysis
Updated:
2013-01-29 13:41:07
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Nutrition RD exam dietetics
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Description:
Domain II, Section A: Screening and Assessment
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  1. Serum Albumin
    • Normal:  3.5- 5.0 g/dl, visceral protein
    • a.  Maintains colloidal osmotic pressure
    • b.  Hypoalbuminemia assoc w/ edema
    • c.  Levels above normal likely due to dehydration
    • d.  Long half-life does not reflect current protein intake
  2. Serum Transferrin
    • Normal > 200 mg/dl visceral protein
    • a.  Serum level controlled by iron storage pool
    • b.  Rises with Ff def
    • c.  Can be determined from TIBC
  3. TTHY
    • Transthyretin, PAB prealbumin
    • Normal 16-40 mg/dl
    • a.  Short half-life
    • b.  Picks up changes in protein quickly
  4. Retinol-Binding Protein RBP
    • Normal 3-6 mg/dL
    • a.  circulates w/ prealbumin
    • b.  Shortest half-life (12 hours)
    • c.  Binds and transports retinol
  5. Hct Hematocrit
    • Normal Men: 44%, Women: 38%, Preg: 33%
    • a.  volume of packed cells in whole blood
  6. Hgb Hemoglobin
    • Normal Men: 14-17mg/dL, Women: 12-15 gm/dL, Preg: <= 11 mg/dL
    • a.  Fe- containing pigment of RBCs
    • b.  Erythrocytes are produced in bone marrow
  7. Serum Ferriting
    • Normal Male: 12-300 ng/mL, Female: 10-150 ng/mL
    • a.  Indicates size of Fe- storage pool
  8. Serum Creatinine
    • Normal 0.6-1.4 mg/dL
    • a.  Related to muscle mass; measures somatic protein
    • b.  May indicate renal disease, muscle wasting
  9. CHI
    • Creatinine Height Index
    • Normal 80%
    • a.  Ratio of creatinine excreted/ 24 hours to height
    • b.  Estimates lean body mass- somatic protein
    • c.  60-80% is mild muscle depletion
  10. BUN
    • Normal 10-20 mg/dL
    • a.  Related to prtein intake
    • b.  Indicator of renal disease
  11. BUN: Creatinine
    Normal 10-15: 1
  12. Urinary Creatinine Clearance
    • Normal 115 +/- 20 ml/ min
    • a.  measures GFR
    • renal function
  13. TLC
    • Total lymphocyte count
    • Normal > 2700 cells/cu mm
    • a,  Measures immunocompetency
    • b.  Moderate depletion 900-1800
    • c.  Severe depletion <900
    • d.  Decreased in protein-energy malnutrition
  14. CRP
    • C-Reactive protein
    • a.  marker of acute inflammatory stress
    • b.  As it declines, indicates when nutrition therapy would be beneficial
  15. FEP
    • Free erythrocyte protoporphyrin
    • a.  Direct measure of toxic effects of lead on heme synthesis
    • b.  Increased in lead poisoning
    • c.  Lead depletes iron leading to anemia and displaces Ca in bone --> Zn def
  16. PT
    • Prothrombin time
    • Normal 11-12.5 seconds; 85-100%
    • a,  anticoagulants prolong PT
    • b.  Evaluates clotting adequacy
    • c.  Change in Vit K intake will alter rate
  17. Hair Analysis
    Not for nutritional assessment.  Useful in measuring intake of toxic metals.

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