MedChem red flag dugs

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Author:
Anonymous
ID:
197469
Filename:
MedChem red flag dugs
Updated:
2013-02-02 19:16:35
Tags:
Red Flag Drugs
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Description:
Red Flag Drugs
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  1. Alendronate
    • Osteoporosis
    • Bisphosphanate
    • prevents resorption of calcium
  2. Bile Acid Sequestrants
    • Hyperlipidemia
    • solid plastic resin
    • prevents bile re absorption
  3. Carbamazepine
    • Anticonvulsant
    • steven johnson syndrome-severe skin reaction
  4. Cimetidine
    GERD
  5. Cisapride-Propulsid
    • GERD
    • QTE elongation
    • compassionate program
  6. Cyclosporine
    • Immunosuppresant
    • st. johns wart-rejection
  7. Digoxin
    • CHF
    • strengthen muscle contractions
    • narrow therapeutic index
  8. Isoniazid
    Anti-tuberculosis agent
  9. Itraconazole
    • Anti-fungal agent
    • potent inhibitor of cyp 3A4
  10. Lithium
    • Manic depressive illness
    • simple salt
    • narrow therapeutic index
  11. Macrolide Antibiotics
    • Erythromycins and others
    • Anti-bacterial agents
    • some are QTE elongators
  12. MAOI Monoamine Oxidase Inhibitor
    Tranylcypromine
    Anti-depressant agent
  13. Oral Contraceptives
    w/antibiotics-kill bacteria in lower colon
  14. Phenobarbital
    • Anticonvulsant
    • Sedative hypnotic
    • w/alcohol=death
  15. Phenytoin
    Anticonvulsant
  16. Protease inhibitors
    HIV/AIDS
  17. Non-nucleoside reverse transcriptase inhibitors
    HIV/AIDS
  18. Reverse transcriptase inhibitors
    HIV/AIDS
  19. Flouroquinolones
    • Antibiotics
    • UTI, STDs, Prostitis
  20. Rifampin
    Anti-tuberculosis agent
  21. Statins
    • Hyperlipidemia
    • lower cholesterol
    • diff drugs in this class eliminated by diff cyp's
  22. St. johns wort
    • depression
    • w/cyclosporin-increases clearance rate
  23. Sucralfate
    Ulcers
  24. Theophylline
    • Asthma bronchodilator
    • Narrow therapeutic index
  25. Warfarin
    • Anti-coagulant
    • prevent blood clot

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