pharma II LA

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Anonymous
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197969
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pharma II LA
Updated:
2013-02-04 20:23:15
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pharma II LA
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pharma II LA
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  1. naturally occuring ester
    LA & vasoconstrictor
    SE - euphoria, abuse potential, cardiotoxic
    uses - topical anesthesia (ophthalmic)
    cocaine
  2. short acting, low hydrophobicity
    uses - infiltration anesthesia in dental work
    ester
    procaine
  3. ester
    long actin, highly potent
    high hydrophobicity
    slow metabolized - gradual release from tissues into bloodstream
    uses - spinal & topical anesthesia
    tetracaine
  4. amide
    rapid onset, medium duration, moderate potency
    uses - infiltration
             peripheral erve block
             epidural
             spinal & topical anesthesia
    lidocaine
  5. amide
    rapid onset, medium duration, moderate potency
    uses - infiltration         
             peripheral nerve block        
             epidural
             spinal and topical anesthesia
    vasoconstrictor
    prilocaine
  6. amide
    highly potent
    highly hydrophobic
    more effects on nociception than locomotor
    uses - spinal, epidural, peripheral block
              used in labor & for post-operative anesthesia
    highly cardiotoxic
    bupivacaine
  7. amide
    less cardiotoxic effects
    levobupivacaine - ropivacaine
  8. order of axon fibers being affected and the result
    • A-delta - pain & temp (stinging)
    • C - second pain & temp (dull)
    • A-gamma - muscle tone
    • A-beta - proprioception
    • A-alpha - motor
  9. 4 ester local anesthetics
    • cocaine
    • procaine
    • chloroprocaine
    • benzocaine
  10. 7 amide local anesthetics
    • lidocaine
    • mepivacaine
    • bupivacaine
    • etidocaine
    • prilocaine
    • ropivacaine
    • articaine
  11. what 3 things could delay onset of a lipophilic drug
    • vasodilating property
    • sequestration if adipose tissue
    • myelin sheaths

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