Lesson 2

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ABO Pheno type is A
What are the possible genotypes

AA, AB, A1A1, A1A2, A2A2, A1O, A2O
ABO Pheno type is B
What are the possible genotypes

BB or BO
ABO Pheno type is AB
What are the possible genotypes

AB, A1B, A2B
ABO Pheno type is O
What are the possible genotypes

OO
In order from greates to least, give those phoenotypes that have the H antigen on their red cells

O, A2, B, A2B, A1, A1B
Which reacts with A1 Lectin?
A1 or A2

Positive agglutination occurs with A1
What causes a weakend D antigen?
- Weak D: RHD mutations. All proteins are present, but antigens are reduced.
- Partial D: Not all epitopes are presnt.
- C in trans to RhD: The allele carrying C(r') is present in trans to (R0r')
What 2 genes are at the Rh genetic locus on Chromosome 1

RHD & RHCE
RhAG glycoprotien does NOT express Rh antigens.

just a fact
A haplotype that produces both c & e (R0) also produce what antigen & why

A haplotype the produces both c & e also produce f. The 3 separate antigens is encoded by a single gene (haplotype).
A person who inherits R1 & R0 will have the c & e antignes on their red cells will not produce what antigen and why?

c & e are on different genes, so they are unable to produce the f antigen