HLA antibody

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Author:
ucstudent01
ID:
198233
Filename:
HLA antibody
Updated:
2013-02-05 20:13:05
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HLA Antibody
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Description:
HLA Antibody
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  1. What antignes are found on Class I on human chromosome 6
    Loci: HLA-A, HLA-B, HLA-C
  2. What antignes are found on Class II on human chromosome 6
    Loci: HLA-DR, HLA-DQ, HLA-DP
  3. What antignes are found on Class III on human chromosome 6
    Loci: COMPLEMENT COMPONENTS
  4. Class I HLA antigens are found on mostly what?
    Nucleated cells
  5. Class II HLA antigens are found on mostly what?
    Bcells, activated T cells, macrophages, monocytes, and endothelial cells
  6. HLA demonstrate what (similar to that of the MNSs system)
    demonstrate linkage disequlibrium
  7. What level should you phenotype at for Solid organs and tissue
    Antigen level
  8. What level should you phenotype for stem cells
    Allele level
  9. For solid organs HLA phenotyping is:
    HLA-A, HLA-B, HLA-DR
  10. For stem cell HLA phenotyping is:
    HLA-A, HLA-B, HLA-C, HLA-DR

    (difference between stem cell and solid organ is: HLA-C)

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