NCLEX- Antilipemic agents

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Gemfibrozil (lopid)

Fibrate. decreases triglyceride level. Increases HDL and decreases LDL.
Fenofibrate (Lofibra)

Fibrate. decreases triglyceride level. Increases HDL and decreases LDL.
Clofibrate (Atromid)

Fibrate. decreases triglyceride level. Increases HDL and decreases LDL.
What does the nurse always need to check and monitor when giving antilipemic (anti lipids) meds?

Base line liver fx because most of them are hepatotoxic
W/ fibrates, why is it important to obtain baseline CK levels?

Because they can cause myopathy.
When should a pt take a fibrate such as gemfibrozil?

30 min prior to breakfast and dinner.
"Statins"

HMG COA reducatase inhibitor. Decreases the manufacture of LDL Cholesterol and increases HDL choleserol.
How should Lovastatin (Mevacor) be taken?

With evening meals.
What category are statins?

Pregnancy risk category X
What food increases levels of statins?

Grapefruit juice.
Ezetimibe (Zetia)

Cholesterol Absorption inhibitor.
What pregnancy category is ezetimibe?

Pregnancy cat x
Colesevelam HCL (WelChol)

Bile acid sequestrant. Decreases LDL cholesterol. Used as adjunct w/ statins.
Cholestyramine (Questran)

Bile acid sequestrant. Decreases LDL cholesterol. Used as adjunct w/ statins.
What is a side effect of Cholestyramine (Questran)

Constipation.
Colestipol (Colestid)

Bile acid sequestrant. Decreases LDL cholesterol. Used as adjunct w/ statins.
Nicotinic Acid
Niacin (Niacor, Niaspan)

Decrease ldl cholesterol and triglyceride levels