What is a non-selective antagonists of A1, A2 in the heart and brain?
What is an antagonist of adenosine of adensosine receptors primarily?
What inhibits the MT growth, orginally used to treat rheumatic complaints and gout?
What binds subunits and prevents their polymerization/growth, currently being investigated on cancer patients?
What give side effects like gastro-intestinal upset and neutropenia? High doses lead to damage bone marrow and anemia?
What can dirupt microfilaments by binding to barbed ends and block elongation, which can inhibit movement and cell division?
What is used for angina to release constricted coronary arteries?
What is normally given when seen signs of subsiding chest pain, decrease of BP, increased HR and orthostatic Hypotension?
What causes glycerol trinitrate to decompose to NO which activates guanylyl cyclase which makes cGMP with the help of a GTP, which will activate PKG, causing the dilation of blood vessels?
What is an anti-neoplastic agent that inhibits MT growth by binding subunits and prevents their polymerization/growth?
What inhibits the enzyme DD-transpeptidase that forms cross - links?
What is used to fight bacterial infection by preventing cell wall synthesis/bacterial growth?
What inhibits DNA gyrase which prevents DNA replication and transcription?
What is an immunosuppressive drug which was recently discovered to prolong life in mice (anti-aging effect)?
What stabilizes MT's in breast cancer therapy?
What has the common side-effects of nausea, vomiting, loss of appetite, change in taste, thinned or brittle hair, pain in the joints of the arms or legs lasting 2-3 days, changes in the color of the nails, and tingling in the hands or toes?
What blocks cGMP phosphodiesterase so it cannot be broken down and stimulates smooth muscle in penis for erection to continue?
What has the side effects of headaches, flushing, dyspepsia, impaired vision, hypotension, loss of hearing, occassional erection lasting more than 24 hrs?
What inhibits MT growth, used to treat certain kinds of cancer like breast, testicular, head and neck cancer, by binding tubulin and M phase cell cycle specific?
What is a mitotic inhibitor by binding to tubulin dimers arresting mitosis in the metaphase - vinca alkaloids therefore affect all rapidly dividing cell types including cancer cells, but also intestinal epithelium and bone marrow?