Drugs/Posions for Block 2

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Author:
rtolly
ID:
198794
Filename:
Drugs/Posions for Block 2
Updated:
2013-02-07 21:17:56
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Medical Drugs posions block Cell Biology
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Drugs/Posions for Block 2 Cell biology
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  1. What is a non-selective antagonists of A1, A2 in the heart and brain?
    Caffeine
  2. What is an antagonist of adenosine of adensosine receptors primarily?


    Caffeine
  3. What inhibits the MT growth, orginally used to treat rheumatic complaints and gout?
    Colchicine
  4. What binds subunits and prevents their polymerization/growth, currently being investigated on cancer patients?
    Colchicine
  5. What give side effects like gastro-intestinal upset and neutropenia? High doses lead to damage bone marrow and anemia?
    Colchicine
  6. What can dirupt microfilaments by binding to barbed ends and block elongation, which can inhibit movement and cell division?
    Cytochalasin B
  7. What is used for angina to release constricted coronary arteries?


    Nitroglycerin
  8. What is normally given when seen signs of subsiding chest pain, decrease of BP, increased HR and orthostatic Hypotension?


    Nitroglycerin
  9. What causes glycerol trinitrate to decompose to NO which activates guanylyl cyclase which makes cGMP with the help of a GTP, which will activate PKG, causing the dilation of blood vessels?
    Nitroglycerin
  10. What is an anti-neoplastic agent that inhibits MT growth by binding subunits and prevents their polymerization/growth?


    Nocodazol
  11. What inhibits the enzyme DD-transpeptidase that forms cross - links?
    Penicillin
  12. What is used to fight bacterial infection by preventing cell wall synthesis/bacterial growth?
    Penicillin
  13. What inhibits DNA gyrase which prevents DNA replication and transcription?


    Quinolones/Fluoroquinolones
  14. What is an immunosuppressive drug which was recently discovered to prolong life in mice (anti-aging effect)?


    Rapamycin
  15. What stabilizes MT's in breast cancer therapy?
    Taxol
  16. What has the common side-effects of nausea, vomiting, loss of appetite, change in taste, thinned or brittle hair, pain in the joints of the arms or legs lasting 2-3 days, changes in the color of the nails, and tingling in the hands or toes?
    Taxol
  17. What blocks cGMP phosphodiesterase so it cannot be broken down and stimulates smooth muscle in penis for erection to continue?
    Viagra
  18. What has the side effects of headaches, flushing, dyspepsia, impaired vision, hypotension, loss of hearing, occassional erection lasting more than 24 hrs?
    Viagra
  19. What inhibits MT growth, used to treat certain kinds of cancer like breast, testicular, head and neck cancer, by binding tubulin and M phase cell cycle specific?
    Vinblastine
  20. What is a mitotic inhibitor by binding to tubulin dimers arresting mitosis in the metaphase - vinca alkaloids therefore affect all rapidly dividing cell types including cancer cells, but also intestinal epithelium and bone marrow?
    Vincristine

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