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  1. a pleuromutilin antibacterial for dermatological use only metabolized by CYP3A4, for S aureus and S pyogenes
  2. purple color gram stain
    gram positive bug
  3. pink color gram stain
    gram negative bug
  4. anti infective MOAs (9)
    • 1)interfere with mucopeptide synthesis
    • 2)prevention of cell wall cross linking
    • 3)prevention of cell wall peptide synth
    • 4)interfere with membrane function
    • 5)disrupt intact membrane integrity
    • 6)disrupt protein synthesis
    • 7)disrupt DNA/mRNA synthesis
    • 8)interruption of microtubules/cell division
    • 9)other yet unknown mechanisms
  5. macrolide for treatment of resistant C difficili
  6. B-lactam antibiotics (classes)
    • penicillins
    • cephalosporins
    • carbapenems
    • monobactams
  7. B-lactam MOA
    transpeptidase prevent the crosslinking of of cell wall component, weakening cell wall
  8. natural penicillin active against most gram+ few gram- for STDs, meningitis, strept, or pneumia. IV or IM use only 60% protein bound
  9. natural penicillin for rhumatic fever lymes disease and mild anarobic infections. oral use 80% protein bound
  10. penicillinase resistant penicillin, first prototype no longer available
  11. penicillinase resistant penicillin for pen-G resistant infections, IM/IV and oral. 90% protein bound, hepatic metabolism, Do NOt Take with meals
  12. penicillinase resistant penicillin for staph infection and osteomylitis, IV/IM or oral route. Do Not admix with anything, 94% protein bound, hepatic metabolism, Do Not take with meal
  13. penicillinase resistant penicillin for any pen-G resistant staph, oral only. 95% protein bound, hepatic metabolism, Do Not take with meals(1-2 hours before).
  14. penicillinase resistant penicillin for any pen-G resistant staph, oral only. 98% protein bound, hepatic metabolism, Do Not take with meals(1-2 hours before).
  15. Aminopenicillian for shigella, salmonella, ecoli, influenza, meningitis, gram+ organisms, staph, strep, and pneumonococci. IM/IV or oral 20% protein bound, Do Not take with meals
  16. aminopenicillin combination for skin, skin structure, intra-abdominal, and gynocological infections. IM/IV, penicillinase resistant, 28/38% protein bound
    Ampicillin and Sulbactam-Unasyn
  17. aminopenicillin similar to ampicillin but more active against shigella, and chlamydia in pregnancy and less diarrhea. oral only 20% protein bound, may take with food
  18. aminopenicillin combination for lower respiratory, otitis media, sinusitis, skin, skin structure infections and UTI. oral only, may take with food, 18/25% protein bound
    amoxicillin and clavulanate- Augmentin

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med chem
2013-02-10 08:59:28
med chem dolence uwyosop

anti infective agents
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