Card Set Information

2013-02-11 20:54:13
Pharm 2A

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  1. Diskus
    Dry powder inhaler
  2. Rotahaler
    Dry powder inhaler
  3. Turbuhaler
    Dry powder inhaler
  4. Albuterol
    Short acting beta 2 agonist (SABA)
  5. Bitolterol
    Short acting beta 2 agonist (SABA)
  6. Pirbuterol
    Short acting beta 2 agonist (SABA)
  7. Formoterol
    Long acting beta 2 agonist (LABA)
  8. Salmeterol
    Long acting beta 2 agonist (LABA)
  9. Terbutaline
    Beta agonist for asthma

    -only used in emergencies (parenteral)
  10. Epinephrine
    Beta and alpha agonist for asthma

    -subcutaneously works but many systemic side effects (BP, HR, arrhythmias, rebound)
  11. Budesonide
    inhaled corticosteroid (ICS) for asthma

    -only ICS available for nebulization
  12. Beclomethasone
    inhaled corticosteroid (ICS) for asthma
  13. Fluticasone
    inhaled corticosteroid (ICS) for asthma
  14. Mometasone
    inhaled corticosteroid (ICS) for asthma
  15. Triamcinolone acetonide
    inhaled corticosteroid (ICS) for asthma
  16. Zafirlukast
    Leukotriene modifier

    -accolate BID - increased hepatotoxicity
  17. Montelukast
    • (Singulair)
    • Luekotriene modifier

    -some reports of suicide risk

    -orally effective with few adverse effects

    -liver metabolism and excreted in bile (feces)
  18. Cromolyn Na & nedocromil
    Mast cell stabilization for asthma (Long Term Control)

    • -short duration of action
    • -non toxic!
    • -similar efficacy to LT antagonist
    • -used as alternative to or in addition to ICS for mild to moderate persistent asthma
  19. Theophylline
    Methylxanthine - 3rd line treatment for asthma (Long Term Control)

    • -similar to caffeine
    • -inhibits phosphodiesterase enzyme
    • -short half life 
    • -narrow therapeutic window
    • -many drug interactions
  20. Xolair
    • (omalizumab)
    • -Anti IgE monoclonal antibody for bad asthma with poor ICS control

    • -subq injection based on IgE levels and weight
    • -for adults and children > 12
    • -AE: pain at injection site, HA, URI
  21. Ipatropium Br
    Quick relief for acute asthma
  22. Bupropion SR
    Nicotine Replacement Therapy (NRT)
  23. Verenicline
    • (Chantix)
    • Nicotine Replacement Therapy (NRT)
  24. Loperamide
    -Opiate for antisecretory agent

    • -not for pts w/ high fever or boody diarrhea; ok for traveler's diarrhea
    • -AE: rare -- dizziness and constipation
  25. Diphenoxylate
    -Opiate use for diarrhea

    • -for acute and chronic diarrhea
    • -combined w/ atropine to discourage abuse
    • -AE: dry mouth, blurred vision, urinary hesitancy
  26. Bismuth subsalicyclate
    (Pepto Bismal)

    -Antosecretoy, anti-inflammatory, and antibacterial effect

    -used for traveler's diarrhea

    -AE: darkening of tongue and stools with repeat administration
  27. Arcapta
    New long acting bronchodilator for COPD
  28. Tiotropium
    First line bronchodilator for stable COPD

    - DPI

    - longer duration than ipatropium bromide
  29. Combivent
    - B2 agonist + anticholinergic for COPD

    - MDI
  30. Duoneb
    - B2 agonist + anticholinergic for COPD

    - solution for inhalation by nebulizer
  31. Aminophylline
    - 2nd line treatment for COPD due to AE

    - bronchodilation via inhibition of enzyme that breaks down cAMP

    • - similar to Theophyllin so many AE (GI, HA, seizures)
    • - requires loading dose
    • - associated w/ arrhytmias and seizures at high dose
  32. Advair

    -inhaled LABA for COPD and asthma
  33. Symbicort

    -inhaled LABA for COPD and asthma
  34. Roflumilast
    • (Daliresp)
    • - new oral tablet for severe COPD pts with chronic bronchitis

    -for severe airflow limitation and hx of exacerbations

    -taken orally daily at the same every day

    -phosphodiesterase 4 inhibitor which reduces lung inflammation