GYN Oncology Test 2/11

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RadiationTherapy
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199437
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GYN Oncology Test 2/11
Updated:
2013-11-18 22:12:26
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radiation oncology gyn female
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GYN Oncology Test 2/11
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  1. Most common histology of cervical ca:
    Squamous cell
  2. Where are cervical ca lesions most likely to arise?
    In the posterior lip of the cervix
  3. Clear cell carcinoma is linked to:
    • DES
    • women whose mothers used DES
  4. Cervical ca peak age:
    50-60 yrs old
  5. 3 common metastasis sites for cervical ca:
    • lungs, bone, liver
    • (hematogenous)
  6. Who sets the staging standards for GYN cancers?
    • FIGO
    • International Federation of Gynecology and Obstetrics 
  7. T-is and T-1 pre-cancerous lesions of the cervix can be treated by:
    Hysterectomy, Cryosurgery, Electrocautery & Laser vaporization
  8. Point A:
    Dose significance?
    Location?
    • Associated with dose to uterus
    • 2cm superior and 2cm lateral to external os
  9. Point B:
    Dose significance?
    Location?
    • Associated with nodal dose
    • 2cm superior and 5cm lateral to external os
  10. Cervical Ca FIGO Staging:
    Carcinoma in situ
    T-is
  11. Cervical Ca FIGO Staging:
    Confined to cervix
    - depth of invasion: 3mm or less
    • T-1a
    • micro-invasive
  12. What is the most radio-sensitive structure?
    the Ovaries
  13. What is the most radio-resistant structure?
    the Endocervix
  14. Cervical Ca FIGO Staging:
    Confined to cervix
    - depth of invasion: greater than 3mm
    • T-1b
    • invasive
  15. Cervical Ca FIGO Staging:
    Extension in to the vagina (upper 2/3)
    - extension in to the vagina
    T-2a
  16. Cervical Ca FIGO Staging:
    Extension in to the vagina (upper 2/3)
    - extension to the parametrium
    T-2b
  17. Cervical Ca FIGO Staging:
    Extension to the lower third vagina/parametrium/pelvic wall
    - extension to the lower third of the vagina
    T-3a
  18. Cervical Ca FIGO Staging:
    Extension to the lower third vagina/parametrium/pelvic wall
    - extension into parametrium & pelvic wall
    T-3b
  19. Cervical Ca FIGO Staging:
    Extension to bladder, rectum or beyond true pelvis
    T-4
  20. What is the most common histology of ovarian ca?
    Epithelial
  21. List four ways ovarian ca can spread?
    • 1. Direct
    • *2. Transcolemic (seeding)*
    • 3. Lymphatic
    • 4. Hematogenous (to liver & lungs)

    *most common
  22. The main lymphatic drainage from the ovaries is into the:
    Para-aortic lymph nodes
  23. The most common sites of metastasis from ovarian ca are?
    Liver & lungs
  24. Overall 5yr survival rate for ovarian ca:
    30%
  25. An elevated level of serum marker ________ may indicate ovarian cancer.
    CA-125
  26. Edema of the abdomen:
    "jelly-belly"
    Ascites
  27. Use of the drug Tamoxifen can lead to:
    Endometrial Ca
  28. Vaginal tumors are most often found:
    on the posterior wall of the upper third of the vagina
  29. _______ cancer can spread along the surface of the uterine cavity.
    Endometrial
  30. The most common histological type of endometrial ca:
    Adenocarcinoma
  31. Overall 5yr survival rate for endometrial ca:
    75%
  32. Vulvar ca in most common in the:
    Labia majora
  33. The most common histological type of vulvar ca:
    Squamous cell
  34. The most common histological type of vaginal ca:
    Squamous cell
  35. Cervical Ca Tx:
    Stage Ia1
    • TAH w/ a small amount of vaginal tissue (vag cuff) or
    • Tandem & Ovoid implant 45-55 Gy to point A
  36. Cervical Ca Tx:
    Stage Ia2
    • TAH w/ more vag tissue or
    • Tandem & Ovoid implant to 70-80 Gy
  37. Cervical Ca Tx:
    Stage Ib1 and IIa
    • TAH 
    • RT (ext beam 45Gy and implant to 80-85Gy)
  38. Cervical Ca Tx:
    Stage IIb - IV
    • RT and
    • Chemotherapy

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