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GYN Oncology Test 2/11
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Most common histology of cervical ca:
Squamous cell
Where are cervical ca lesions most likely to arise?
In the posterior lip of the cervix
Clear cell carcinoma is linked to:
DES
women whose mothers used DES
Cervical ca peak age:
50-60 yrs old
3 common metastasis sites for cervical ca:
lungs, bone, liver
(hematogenous)
Who sets the staging standards for GYN cancers?
FIGO
International Federation of Gynecology and Obstetrics
T-is and T-1 pre-cancerous lesions of the cervix can be treated by:
Hysterectomy, Cryosurgery, Electrocautery & Laser vaporization
Point A:
Dose significance?
Location?
Associated with dose to uterus
2cm superior and 2cm lateral to external os
Point B:
Dose significance?
Location?
Associated with nodal dose
2cm superior and 5cm lateral to external os
Cervical Ca FIGO Staging:
Carcinoma in situ
T-is
Cervical Ca FIGO Staging:
Confined to cervix
- depth of invasion: 3mm or less
T-1a
micro-invasive
What is the most radio-sensitive structure?
the Ovaries
What is the most radio-resistant structure?
the Endocervix
Cervical Ca FIGO Staging:
Confined to cervix
- depth of invasion: greater than 3mm
T-1b
invasive
Cervical Ca FIGO Staging:
Extension in to the vagina (upper 2/3)
- extension in to the vagina
T-2a
Cervical Ca FIGO Staging:
Extension in to the vagina (upper 2/3)
- extension to the parametrium
T-2b
Cervical Ca FIGO Staging:
Extension to the lower third vagina/parametrium/pelvic wall
- extension to the lower third of the vagina
T-3a
Cervical Ca FIGO Staging:
Extension to the lower third vagina/parametrium/pelvic wall
- extension into parametrium & pelvic wall
T-3b
Cervical Ca FIGO Staging:
Extension to bladder, rectum or beyond true pelvis
T-4
What is the most common histology of ovarian ca?
Epithelial
List four ways ovarian ca can spread?
1. Direct
*2. Transcolemic (seeding)*
3. Lymphatic
4. Hematogenous (to liver & lungs)
*most common
The main lymphatic drainage from the ovaries is into the:
Para-aortic lymph nodes
The most common sites of metastasis from ovarian ca are?
Liver & lungs
Overall 5yr survival rate for ovarian ca:
30%
An elevated level of serum marker ________ may indicate ovarian cancer.
CA-125
Edema of the abdomen:
"jelly-belly"
Ascites
Use of the drug Tamoxifen can lead to:
Endometrial Ca
Vaginal tumors are most often found:
on the posterior wall of the upper third of the vagina
_______ cancer can spread along the surface of the uterine cavity.
Endometrial
The most common histological type of endometrial ca:
Adenocarcinoma
Overall 5yr survival rate for endometrial ca:
75%
Vulvar ca in most common in the:
Labia majora
The most common histological type of vulvar ca:
Squamous cell
The most common histological type of vaginal ca:
Squamous cell
Cervical Ca Tx:
Stage Ia1
TAH w/ a small amount of vaginal tissue (vag cuff) or
Tandem & Ovoid implant 45-55 Gy to point A
Cervical Ca Tx:
Stage Ia2
TAH w/ more vag tissue or
Tandem & Ovoid implant to 70-80 Gy
Cervical Ca Tx:
Stage Ib1 and IIa
TAH
RT (ext beam 45Gy and implant to 80-85Gy)
Cervical Ca Tx:
Stage IIb - IV
RT and
Chemotherapy
Author
RadiationTherapy
ID
199437
Card Set
GYN Oncology Test 2/11
Description
GYN Oncology Test 2/11
Updated
11/19/2013, 3:12:26 AM
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