Ch. 10 Iron Def. Anemias

Card Set Information

Author:
Angela6
ID:
199525
Filename:
Ch. 10 Iron Def. Anemias
Updated:
2013-02-10 20:33:55
Tags:
Hematology
Folders:

Description:
Iron Deficiency Anemia and Anemia of Chronic Inflammation
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user Angela6 on FreezingBlue Flashcards. What would you like to do?


  1. Iron Deficiency Anemia
    Is the most common anemias worldwide
  2. Causes of Iron Deficiency Anemia:
    • Nutritional deficiency
    • GI disease
    • Increased demand for erythropoiesis
    • Excess iron loss (excessive bleeding)
  3. Types of iron anemias:
    • Sideroblastic anemias
    • Chronic inflammation
    • Decreased plasma transferrin
  4. When does the demand for iron increase?
    • Pregnancy
    • Menustration
    • Growth
  5. How many grams of iron per person?
    • 3-5
    • Conservation of iron is normally very efficient
  6. Iron need in infants and children:
    • Full term infants have 4 months iron storage.
    • 50% iron absorption from human milk
  7. Milk anemia
    Occur in infants that depend solely on cow's milk.
  8. Diet Iron:
    • 90% of dietary iron is non-heme
    • 10% heme iron is well absorbed.
  9. Factors that increase non-heme iron absorption:
    Meats, ascorbic acid (OJ)
  10. Factors that decrease non-heme iron absorption
    Vegetable fibers and tea
  11. Ingested ferric iron (Fe3+) is reduced to __________ iron by stomach acid.
    ferrous (Fe2+)
  12. Where is most iron absorbed?
    Upper jejunum
  13. __________ delivers iron to bone marrow.
    Transferrin
  14. Papillodema:
    Dents in forehead of infants
  15. PICA syndrome:
    Eat dirt, weird things
  16. Labs of iron deficiency anemia:
    • Decreased RBC, HGB, HCT, MCH,MCHC, MCV
    • Hypochromic-Microcytic RBCs
    • WBC=normal
    • Platelets=Normal to increased
    • Total serum iron=decreased
    • TIBC=Increased
    • %Fe saturation=Decreased
    • Plasma ferritin= Decreased

    Decreased plasma ferritin is the best single test, and earliest, indication of iron deficiency.
  17. Iron deficiency anemia
    • Severe iron anemia
    • Teardrops and elliptocytes (common in Fe deficiency)
  18. Anemias of Inflammation or Chronic Disorders:
    • Associated with chronic inflammatory conditions (RA, SLE, Cancers,Liver and renal diseases)
    • Not an iron deficiency.
  19. Labs of (ACD)
    • Mild anemia.
    • Normal to hypo-micro RBC morphology
    • Decreased=plasma iron and TIBC
    • Increased=plasma ferritin
  20. Sideroblastic Anemias
    • Ineffective erythropoiesis with excess iron accumulation in the mitochrondia or bone marrow precurssors.
    • Iron is "trapped" in cytoplasma
  21. Sideroblastic anemia causes:
    • Genetic
    • Leukemias
    • Drug/Toxins
    • Myelodysplastic syndromes
  22. Sideroblastic anemia labs:
    • 10-40% ringed sideroblasts in the bone marrow.
    • Hypochromic-microcytic RBCs
    • Basophilic stippling, target cells, dimorphic RBCs.

    INCREASED=Plasma iron, TIBC, Ferritin
  23. (HH) Hereditary Hemochromatosis:
    • Genetic (autosomal recessive) disorder of excessive GI iron absorption.
    • Excess iron accumulations in the tissues can cause damage.
    • Common in Celtic ancestry.
    • 1 in 10 persons are estimated to carry the gene.

    INCREASED=Plasma ferritin, transferrin saturation

    Treated by therapeutic phlebotomy (removes iron)
  24. Top 10
    • Iron deficiency is common.
    • Iron conservation prevents loss of iron.
    • Hypo-Micro anemia
    • Transferrin: Iron transport plasma protein
    • Ferritin: Iron storage molecule
    • Sideroblastic anemias: Iron trapped in marrow NRBCs
    • Hemochromatosis: excess iron
    • Anemias of inflammation: Iron not released from RE system

What would you like to do?

Home > Flashcards > Print Preview