Most common cause of bloody nipple d/c• Diffuse papillomatosis has increased risk of cancer
Intraductal Papilloma – not premalignant
Nonspontaneous, B/L, multiple ducts,greenish, milky is likely benign.
– S. Aureus, other bacteria (e.g. Strep)
– Inflammatory Breast Cancer
Breast skin - Painful, cordlike superficial thrombophlebitis
– FIBROCYSTIC CHANGES
– NO INCREASED RISK
– 1-2X INCREASED RISK OF CANCER
– ATYPICAL HYPERPLASIA
– 4-5X INCREASED RISK OF CANCER
Found in 3% of benign breast biopsies.
Associated w/ 13% subsequent development of breast cancer (4x risk factor)
Some may be an under-diagnosed ductal carcinoma in situ
Excisional Biopsy – do not need clear margins
Atypical Hyperplasia - Marked proliferation and atypia of the epithelium, either