Micro 265

Microscope builder and observed animolecules

Disease caused by invisible creatures

spontaneous generation

Cheesecloth on meat stopped maggots

Boiled broth sealed in jars still became turbid

Sealed flasks of broth boiled and didn't become turbid= air required for microbes

First to connect cause and effect, discovered fermentation, nature of disease and spontaneous generation

methods and principles for isolation and pure bacterial cultures, proved cause of disease and discovered cause of tuberculosis

• pathogen growth on culture: 
• required complex nutrients from host
• slow growing organisms fail
• organisms that can't grow on selected media fail

Pure culture isolation on agar petri dishes

Smallpox Vaccine

Founder of bacteriology

Concept of chemolithotrophy and autotrophy

enrichment culturing method and concept of a virus

Discovery of penicillin

Prod of penicillin on industrial scale

Discovery of streptomycin in soil bacteria foundation of modern pharmaceutical industry

Discovery of bacteria in boiling hotsprings - isolated Thermus aquaticus

Discovery of archaea

1st complete sequence of bacterial genome