Card Set Information
what are the glycoproteins on HIV envelope?
together make GP 160
what type of virus is HIV?
2single stranded RNA
what are the ways of transmission of HIV?
: concurrent STI
: IVDU, blood product
: delivery or breast feed
how is vertical transmission of HIV prevented?
1. HAART to pregnant woman
2. C-section to control blood contact at delivery
3. stop breast feeding
give 7 features of primary HIV infection presentation?
: blanching erythematous
meningitis, other neuro
: GB, transverse myelitis, mononeuritis
what is the spectrum of AIDS? give 3 categories
: KS, lymphoma, viral oncogenesis, castleman's disease
HIV direct effect
: enteropathy, dementia, nephropathy
name the bacterial infections in AIDS and what they cause
: pneumonia, meningitis, sepsis
name the mycobacterial infections in AIDS and what they cause
: pulmonary, meningitis, disseminated lymphadenitis
M. Avium intracellulare
: disseminated lymphadenitis, GI infection
name the fungal infections in AIDS and what they cause
Pneumocystis jiroveci (PCP)
: upper GI infection
cryptococcus neoformans (soil)
: fever, meningitis, skin lesion
name the different herpes virus infections in AIDS and what they cause
: oral ulcers - cold sores. all way through mucosal layers, meningoencephalitis
: genital ulcers
: recurrent chickenpox and shingles (multidermatomal)
: fever, retinitis, gastroenteritis,
: hairy leukoplakia
: Kaposi's sarcoma, Castleman's disease
name the protozoan infections in AIDS and what they cause
: cerebral abscess, retinitis, disseminated (inadequ prep food)
: fever, hepatosplenomegaly, lymphadenopathy (bite of a sandfly)
what is slim's disease and what are the main causes of it in HIV?
: CMV, MAI, cryptosporidiosis, microsporidiosis
: lymphoma, KS
what are the causes of lymphadenopathy in HIV?
: mTb, MAI, leishmania, histoplasmosis
: lymphoma, KS, castleman's
: immune activation
what are the different skin diseases in HIV?
what are the GI tract diseases in HIV?
KS in mouth
HSV oral ulcers
name 2 ano genital disorders in HIV
HSV2 genital ulcers
papilloma virus causing perianal warts
what are the different respiratory diseases in HIV?
pneumocystis jiroveci (PCP)
KS in airways
lymphadenopathy due to TB or lymphoma
what are the near diseases of HIV?
atrophy and dementia
peri ventricular lymphoma
: Strep pneumo, HSV, TB
progressive multi leukoencephalopathy
: plaques of demyelination
what are the haematological diseases in HIV?
how is consent obtained for a HIV test?
1. no obligation
: if pick up can treat earlier and prevent from getting worse
3. simple blood test
if a pt is unable to give consent but HIV is suspected, what happens?
: do not ask family/partner
pts best interest
what are the 2 main types of tests for HIV?
: anti-gp120, p24 antigen
: RNA HIV viral load, proviral DNA