NCLEX- Endocrine DB

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Reg insulin onset

0.5 5o 1 hour
Humalog onset

15 min
NPH onset

1 to 2 hours
Tolbutamide (Orinase)

Sulfonylureas. Results in insulin release from pancrease
Glipizide (Glucotrol)

Sulfonylureas. Results in insulin release from pancrease
Clients taking Glipizide (glucotrol) should be cautioned from consuming what?

alcohol. can cause a disulfiram- like reaction (intense n, v, flushing and palpitations).
Repaglinide (Prandin)

Meglitinides. Results in insulin release from pancreas
When should a pt take Repaglinide (prandin)?

30 minutes before the clients eats.
Metformin (Glucophage)

Biguanides. Reduces production of glucose w/in the liver through supression of gluconeogenesis and increases muscles' glucose uptake and use
Pt's taking Metformin (Glucophage) should be monitored for what?

Lactic Acidosis.
Rosiglitazone (Avandia)

Thiazolidineidiones (Glitazones). Decreases insulin resistance. Increases gluocse uptake and production
Acarbose (Precose)

Alpha glucosidase inhibitors. slows carb absorption and digestion
Sitagliptin (januvia)

Gliptin. promotes release of insulin and decreases glucagon. lowers postprandial blood glucose levels.
Pramlintide (Symlin)

Amylin mimetic. Decreases postprandial glucose levels. Delays gastric emptying
What does the client need to be informed about Pramlintide (symlin)

Because the med causes delayed gastric emptying, take oral medis before injecting Pramlintide and discard open vials after 28 days.
Incretin Mimetics

Exenatide (Byetta). Delays gastric emptying lower postprandial glucose levels. Give 60 min before evening or morning meal.
What is a side effect of Glucagon?

GI distress (N, V). Turn clients to left side foloowing administration.

Author:	Gandrews
ID:	201020
Card Set:	NCLEX- Endocrine DB
Updated:	2013-02-17 00:18:59
Tags:	NCLEX Endocrine DB
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Description:	NCLEX- Endocrine DB
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