Week 6 Crossmatch Results
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Antibody Screen: IS & AHG = Neg
- With 4+ reaction, most likely cause is:
- ABO incompatibility (wrong type selected)
AB Screen: IS & AHG = Neg
Crossmatch: IS = 0 & AHG = 1+
- 1: Donor has + DAT because AHG phase is incompatible
- 2: Pt has antibody to low freq antigen that was not present on screen cells, but present on donor.
- 3: Pt has antibody showing dosage: it reacts better with homozygous cells rather than heterozygous. (screen has heterozygous expression while donor has homozygous)
- 4:Patient my have recieved plasma incompatible products and has a passive ABO antobody that is reacting with the donor RBC's.
AB Screen: IS Neg & AHG screen II 1+
- 1: Patient probably has an antibody where the donor unit is lacking the corresponding antigen.
- 2: Screen cells exhibit dosage (homozygous cells) while the donor is heterozygous.
AB Screen: IS = neg & AHG = 2+ both cells
Crossmatch: IS = Neg & AHG = 2+
Patient probably has an alloantibody. The donor probably has the antigen that the patient has made an antibody against.
AB Screen: Positive
Auto Control: Positive
- 1: Most likely is AUTOANTIBODY. Autos typically react in all phases.
- 2: Alloantibody (MF Reaction) (will only occur if patient recently transfused)
- 3: Rouleax (false agglutination)
- 4: Reagent related (pt. may have antibodies to addatives in reagents like liss or alb)
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